Table 1 General characteristics of included subjects
Characteristic | Based on loop gain > 0.7 | |||
|---|---|---|---|---|
Overall N = 10551 | Low N = 711 (67%)1 | High N = 344 (33%)1 | p-value2 | |
Loop gain (dimensionless) | 0.65 (0.21) | 0.54 (0.11) | 0.88 (0.16) | < 0.001 |
Demographics, social and family history | ||||
Age (y) | 55 (15) | 54 (15) | 58 (14) | < 0.001 |
Female sex | 465 (44%) | 332 (47%) | 133 (39%) | 0.014 |
BMI (kg/m2) | 33 (9) | 33 (9) | 33 (8) | 0.8 |
Race | 0.5 | |||
White | 617 (58%) | 410 (58%) | 207 (60%) | |
Black | 76 (7.2%) | 48 (6.8%) | 28 (8.1%) | |
Asian | 88 (8.3%) | 64 (9.0%) | 24 (7.0%) | |
Other/unclear | 274 (26%) | 189 (27%) | 85 (25%) | |
Current smoking | 69 (6.5%) | 47 (6.6%) | 22 (6.4%) | > 0.9 |
Current alcohol use | 456 (43%) | 304 (43%) | 152 (44%) | 0.7 |
OSA family history | 104 (9.9%) | 68 (9.6%) | 36 (10%) | 0.7 |
Co-morbidities and medications | ||||
Hypertension | 488 (46%) | 315 (44%) | 173 (50%) | 0.075 |
Heart failure | 65 (6.2%) | 41 (5.8%) | 24 (7.0%) | 0.5 |
Arial fibrillation | 74 (7.0%) | 48 (6.8%) | 26 (7.6%) | 0.6 |
Prior stroke | 32 (3.0%) | 23 (3.2%) | 9 (2.6%) | 0.7 |
Oxygen use | 45 (4.3%) | 29 (4.1%) | 16 (4.7%) | 0.7 |
Ticagrelor | 6 (0.6%) | 1 (0.1%) | 5 (1.5%) | 0.016 |
Data from the polysomnography-report | ||||
AHI (/h) | 35 (29) | 29 (26) | 46 (32) | < 0.001 |
SpO2 nadir (%) | 80 (9) | 81 (9) | 79 (11) | 0.001 |
SpO2 mean (%) | 93.50 (2.53) | 93.7 (2.41) | 93.1 (2.75) | 0.002 |
Percent hypopneas (%) | 70 (27) | 75 (24) | 59 (29) | < 0.001 |
Mean event duration (s) | 24 (6) | 24 (6) | 22 (6) | < 0.001 |
Total arousal index (/h) | 30 (24) | 26 (20) | 37 (28) | < 0.001 |
Log-AHIREM/NREM-ratio3 | 0.20 (1.18) | 0.29 (1.25) | 0.01 (1.00) | < 0.001 |