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Table 4 Comparison of the different lymphocyte subsets before and after treatment in the immunotherapy effective and ineffective groups

From: Association of lymphocyte subsets with efficacy and prognosis of immune checkpoint inhibitor therapy in advanced non-small cell lung carcinoma: a retrospective study

 

Effective group

Ineffective group

Before

After

P

Before

After

P

CD4+

35.78 ± 8.86

42.09 ± 9.46

 < 0.001

31.27 ± 10.79

30.41 ± 8.12

0.486

CD8+

32.51 ± 10.51

23.63 ± 7.72

 < 0.001

35.69 ± 11.93

36.44 ± 10.9

0.425

CD4+/CD8+

1.47 ± 2.48

2.10 ± 1.29

0.010

1.00 ± 0.48

0.95 ± 0.53

0.442

NK

21.28 ± 10.49

23.78 ± 9.05

0.003

17.30 ± 9.88

18.75 ± 12.01

0.346

Tregs

6.77 ± 1.81

7.61 ± 2.38

0.001

5.64 ± 1.82

5.93 ± 1.98

0.394

B

8.31 ± 4.19

7.36 ± 4.64

0.132

8.15 ± 4.68

7.65 ± 4.14

0.630