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Table 2 Comparison of patients with respiratory involvement and non- respiratory involvement

From: Comparison of relapsing polychondritis patients with and without respiratory involvement based on chest computed tomography: a retrospective cohort study

Variables

All patients

(n = 72)

Non-airway involvement

(n = 29)

Airway involvement

(n = 43)

p value

Male

42(58.3%)

19(65.5%)

24(55.8%)

0.26

Smoke

29(40.3%)

11(37.9%)

18(41.9%)

0.73

Age at the time of first symptoms (years)

54.03 ± 13.10

56.36 ± 16.18

52.48 ± 10.71

0.39

The time of the first symptom to the diagnosis (months)

6(2–24)

4.5(2–15)

7(2–24)

0.52

Age at diagnosis(years)

55.20 ± 12.59

57.29 ± 15.44

53.81 ± 10.45

0.43

Laboratory findings

IgG (mg/dl)

1139.82 ± 317.57

1062.2 ± 307.62

1187.87 ± 321.38

0.27

IgA (mg/dl)

272.5(182.5–370.25)

266(93.45–318)

277(190.5–405.5)

0.40

IgM (mg/dl)

78..35(61.45–130.25)

73.1(61.75–114.55)

82.8(60.2–132)

0.68

C3 (mg/dl)

109.72 ± 21.34

102.86 ± 18.31

113.97 ± 22.38

0.14

C4 (mg/dl)

28.8(22.45–34.18)

25.61 (22–30.65)

29.31(22.3–35.75)

0.26

Albumin (g/L)

36.31 ± 5.80

37.04 ± 7.36

35.85 ± 4.73

0.57

Total cholesterol (mmol/l)

4.23(3.85–5.09)

4.67(3.72–5.09)

4.12(3.83–5.11)

0.62

HDL-C (mmol/l)

1.1(0.8–1.59)

1.1(0.87–1.65)

1.02(0.77–1.54)

0.51

LDL-C (mmol/l)

2.75(2.48–3.32)

2.8(2.2–3.1)

2.72(2.53–3.77)

0.68

Triglyceride (mmol/l)

1.04(0.8–1.23)

1.09(0.85–1.34)

0.98(0.74–1.11)

0.08*

LDH (u/l)

190.5(158.75–216.25)

191(170–214.5)

190(140.5–229)

0.83

Creatinine (umol/l)

61.1(49.13–70.13)

69.8(50.5–79.35)

55.8(44.35–66.25)

0.02*

Uric acid (umol/l)

266.85 ± 89.99

320.15 ± 88.02

233.88 ± 75.66

0.01*

HbA1c (%)

5.95(5.52–7.34)

5.9(5.51–7.45)

6(5.55–7.57)

0.62

White blood cells (10^9)

8.06(6.54–10.05)

7.18 (5.64–10.66)

8.16 (7.04–9.57)

0.4

Neutrophils (10^9)

5.77(4.23–7.58)

5.61(3.05–7.07)

6.21(4.51–8)

0.23

Lymphocyte (10^9)

1.48(0.87–2.19)

1.85 (0.99–2.86)

1.32 (0.87–2.01)

0.29

Monocyte (10^9)

0.47 (0.41–0.66)

0.43 (0.38–0.72)

0.47 (0.44–0.68)

0.4

Hemoglobin (g/l)

124.4 ± 21.8

122.38 ± 28.68

123.95 ± 14.87

0.84

Platelet (10^9)

289.5(190.75–355.02)

245(175–311)

298(267.5–376.5)

0.15

CRP (mg/l)

2.31(0.61–8.19)

0.96(0.43–4.50)

3.96(1.74–9.78)

0.03*

ESR (mm/h)

25.5(13.75–44)

20 (13–28)

30(14–60.5)

0.04*

CAR

0.07(0.19–0.26)

0.23(0.14–0.11)

0.11(0.04–0.29)

0.04*

NLR

4.26(1.78–7.06)

1.80(1.47–6.08)

4.46(3.02–9.05)

0.03*

PLR

197.59(124.29–286.34)

132.43(76.10)-202.32

223.08(185.8–7-334.14)

0.01*

Outcomes

Mortality

5(6.9%)

2(6.9%)

3(7%)

0.72

  1. Data are presented as median (interquartile range), mean (standard deviation) or n (%)
  2. HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; LDH, lactate dehydrogenase; CRP, c-active protein; ESR, erythrocyte sedimentation rate; CAR, C reactive protein to albumin ratio; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio
  3. *p < 0.05