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Fig. 7 | BMC Pulmonary Medicine

Fig. 7

From: Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis

Fig. 7

Sevoflurane ameliorates LPS-induced ALI by modulating the LncRNA LINC00839/miR-223/NLRP3 axis. Sevoflurane diminishes LPS-induced upregulation of LINC00839/NLRP3, leads to inactivation of caspase-1 and reduction of pro-inflammatory factor (IL-1β and IL-18), and suppresses pyroptosis and inflammation, thereby ameliorating LPS-induced ALI

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