Table 4 Suggested C-reactive protein (CRP) cut-off values to predict bacterial versus non-bacterial AECOPD
Author | Setting | Number of Exacerbations | Number of Exacerbations with Bacterial Cause | Cut-off / mg/L | Sensitivity / % | Specificity / % | Positive Predictive Value / % | Negative Predictive Value / % |
|---|---|---|---|---|---|---|---|---|
Bafadhel [39] | OP | 158 | 84 | 10 | 60 | 70 | – | – |
Bircan [25] | H | 51 | – | 10 | 72.5 | 100 | – | – |
Hassan [19] | H | 30 | 22 | 15 | 95.5 | 100 | – | – |
Peng [21] | H | 81 | 55 | 19.65 | 78 | 85 | – | – |
Peng (with mucoid sputum) |  |  |  | 15.21 | 81 | 77 | – | – |
Sethi [46] | OP | 150 | 84 | 2.37 | 61.8 | 68.3 | 39.6 | 84.1 |
Tanriverdi [13] | ICU | 77 | 28 | 1.5 | 54 | 52 | – | – |
|  |  |  |  | 42 | 82 | 35 | – | – |
|  |  |  |  | 110 | 35 | 80 | – | – |
Van de Geijn [37] | H | 45 | 22 | 5 | 91 | 39 | – | – |
Xiong [35] | H | 78 | 38 | 31.68 | 68.42 | 85.00 | 89.81 | 58.35 |