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Table 1 Demographic and deployment characteristics and pulmonary function in controls and symptomatic deployers overall and by diagnostic sub-group

From: Quantitative imaging analysis detects subtle airway abnormalities in symptomatic military deployers

 

Controls

n = 45

Deployers

n = 82

p-value*

Definite

n = 45

Possible

n = 37

p-value**

Demographic characteristics

  Age (years)

58.1

(± 6.7)

42.0

(± 10.2)

 < 0.0001

39.4

(± 9.2)

45.2

(± 10.5)

 < 0.0001abc

 Male

37 (82%)

71 (87%)

0.51

40 (89%)

31 (84%)

0.65

 Smoking status

      

  Never

28 (62%)

56 (68%)

0.74

33 (73%)

23 (62%)

0.77+

  Former

13 (29%)

21 (26%)

10 (22%)

11 (30%)

 Current

4 (9%)

5 (6%)

2 (4%)

3 (8%)

 Pack-years

25.8

(± 21.8)

8.4

(± 13.0)

0.007

5.2

(± 3.6)

11.2

(± 17.3)

0.006

 BMI (kg/m2)

28.1

(± 6.2)

31.0

(± 5.0)

0.01

30.4

(± 5.0)

31.6

(± 5.0)

0.01

Deployment characteristics

 Median (range) number of deployments

2 (1–11)

2 (1–11)

2 (1–7)

 Total deployment duration (months)

23.5

(± 20.7)

20.1

(± 22.4)

24.7

(± 24.4)

Pulmonary function testing^

 FVCPP

94.7

(± 12.2)

91.7

(± 12.6)

0.20

91.0

(± 13.3)

92.7

(± 11.9)

0.36

 FEV1PP

93.8

(± 14.8)

90.8

(± 15.1)

0.29

90.4

(± 17.1)

91.2

(± 12.3)

0.55

 FEV1/FVC ratio (%)

76.0

(± 8.0)

78.8

(± 7.5)

0.05

79.4

(± 8.1)

78.1

(± 6.7)

0.11

 RVPP

106.1

(± 20.9)

105.8

(± 20.4)

106.4

(± 21.9)

 TLCPP

103.8

(± 12.4)

101.8

(± 11.2)

106.5

(± 13.5)

 RV/TLC ratio (%)

30.9

(± 5.5)

30.8

(± 5.6)

31.0

(± 5.5)

 DLCOPP

115.3

(± 20.6)

116.5

(± 20.3)

113.6

(± 21.1)

  1. Bold values are statistically significant
  2. Results are the number (%) or mean (± standard deviation) unless otherwise noted
  3. *Deployers and controls were compared using t-tests for continuous variables (Satterthwaite result) and Chi-square tests for categorical variables. Statistically significant p-values are bolded if < 0.006, adjusting for multiple comparisons (8 tests) with a Bonferroni correction
  4. **Diagnostic groups were compared using ANOVA for continuous variables and Chi-square or Fisher Exact tests (indicated by +) for categorical variables. Statistically significant p-values are bolded if < 0.006, adjusting for multiple comparisons (8 tests) with a Bonferroni correction. Individual comparisons between groups were performed if the overall test was significant after Bonferroni correction with the following designations for significant differences (p < 0.05): adefinite vs controls, bpossible vs controls, cdefinite vs possible
  5. ^One control is missing spirometry data. Spirometry values are all pre-bronchodilator and include the Forced Vital Capacity percent predicted (FVCPP), Forced Expiratory Volume in one second (FEV1PP), and the FEV1/FVC ratio. Residual volume percent predicted (RVpp) and total lung capacity percent predicted (TLCPP) were available for 76 deployers, and diffusion capacity for carbon monoxide percent predicted (DLCOpp) was available for 75 deployers