From: Quantitative imaging analysis detects subtle airway abnormalities in symptomatic military deployers
Controls n = 45 | Deployers n = 82 | p-value* | Definite n = 45 | Possible n = 37 | p-value** | |
---|---|---|---|---|---|---|
Demographic characteristics | ||||||
Age (years) | 58.1 (± 6.7) | 42.0 (± 10.2) | < 0.0001 | 39.4 (± 9.2) | 45.2 (± 10.5) | < 0.0001abc |
Male | 37 (82%) | 71 (87%) | 0.51 | 40 (89%) | 31 (84%) | 0.65 |
Smoking status | ||||||
Never | 28 (62%) | 56 (68%) | 0.74 | 33 (73%) | 23 (62%) | 0.77+ |
Former | 13 (29%) | 21 (26%) | 10 (22%) | 11 (30%) | ||
Current | 4 (9%) | 5 (6%) | 2 (4%) | 3 (8%) | ||
Pack-years | 25.8 (± 21.8) | 8.4 (± 13.0) | 0.007 | 5.2 (± 3.6) | 11.2 (± 17.3) | 0.006 |
BMI (kg/m2) | 28.1 (± 6.2) | 31.0 (± 5.0) | 0.01 | 30.4 (± 5.0) | 31.6 (± 5.0) | 0.01 |
Deployment characteristics | ||||||
Median (range) number of deployments | – | 2 (1–11) | – | 2 (1–11) | 2 (1–7) | – |
Total deployment duration (months) | – | 23.5 (± 20.7) | – | 20.1 (± 22.4) | 24.7 (± 24.4) | – |
Pulmonary function testing^ | ||||||
FVCPP | 94.7 (± 12.2) | 91.7 (± 12.6) | 0.20 | 91.0 (± 13.3) | 92.7 (± 11.9) | 0.36 |
FEV1PP | 93.8 (± 14.8) | 90.8 (± 15.1) | 0.29 | 90.4 (± 17.1) | 91.2 (± 12.3) | 0.55 |
FEV1/FVC ratio (%) | 76.0 (± 8.0) | 78.8 (± 7.5) | 0.05 | 79.4 (± 8.1) | 78.1 (± 6.7) | 0.11 |
RVPP | – | 106.1 (± 20.9) | – | 105.8 (± 20.4) | 106.4 (± 21.9) | – |
TLCPP | – | 103.8 (± 12.4) | – | 101.8 (± 11.2) | 106.5 (± 13.5) | – |
RV/TLC ratio (%) | – | 30.9 (± 5.5) | – | 30.8 (± 5.6) | 31.0 (± 5.5) | – |
DLCOPP | – | 115.3 (± 20.6) | – | 116.5 (± 20.3) | 113.6 (± 21.1) | – |