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Table 7 Parameter estimates from multiple linear regression analyses for air trapping quantitative imaging measurements (n = 107)

From: Quantitative imaging analysis detects subtle airway abnormalities in symptomatic military deployers

Variable

Comparison group or increase

Parameter estimate [95% confidence interval] (p-value)*

Change in E/I TLV ratio

Change in E/I MLD ratio

Change in LAA%-856 (%)

Intercept

 

0.4 [0.3, 0.6]

0.7 [0.7, 0.8]

 10.6 [ 20.6,  0.6]

Deployer

Control

0.01 [−0.2, −0.06]

(p < 0.0001)

0.05 [−0.08, −0.02] (p = 0.0008)

 1.1 [ 4.4, 2.2] (p = 0.51)

Male

Female

 0.004 [ 0.05, 0.04]

(p = 0.87)

 0.002 [ 0.03, 0.02] (p = 0.90)

 3.0 [ 6.2, 0.3] (p = 0.07)

Age

 + 1 year

0.003 [0.001, 0.005]

(p = 0.003)

0.003 [0.002, 0.004]

(p < 0.0001)

0.1 [ 0.01, 0.3] (p = 0.07)

Smoking pack years

 + 1 pack year

 0.0006 [ 0.002, 0.0008]

(p = 0.39)

 0.0001 [ 0.0009, 0.0006]

(p = 0.73)

0.07 [ 0.01, 0.2] (p = 0.09)

BMI

 + 1 kg/m2

 0.002 [ 0.006, 0.0007]

(p = 0.13)

0.003 [−0.005, −0.0008]

(p = 0.006)

 0.2 [ 0.4, 0.05] (p = 0.13)

TLV (expiratory)

 + 1 L

6.9 [4.7, 9.0] (p < 0.0001)

  1. Bold values are statistically significant
  2. *Results are the p-value from the F-test using a linear model with all covariates included at the same time