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Table 2 Characteristics of groups of patients with and without radiographic ILA/ILD patterns in the cohort (N = 352)

From: Interstitial lung abnormalities and interstitial lung diseases associated with cigarette smoking in a rural cohort undergoing surgical resection

Variables, values, n (%) or mean ± SD

Group with ILA-ILD (N = 186, 52.8%)

No ILA-ILD (N = 166, 47.2%)

Total cohort (N = 352)

p value

Age

66.94 ± 9.35

65.28 ± 11.02

66.15 ± 10.19

0.141

Gender (male)

81 (22.8)

70 (19.9)

151 (42.9)

0.838

Body mass index (BMI, kg/m2)

28.19 ± 6.68

28.54 ± 7.1

28.35 ± 6.88

0.660

Race (White)

181 (51.3)

158 (45)

339 (96.3)

0.294

Smoking status:

    

 1. Ever-smoker

173 (49)

140 (39.9)

313 (88.9)

0.010

 2. Pack years

44.57 ± 34.96

34.96 ± 26.22

43.23 ± 31.86

0.005

Comorbidities

    

 1. COPD

123 (35)

93 (26.4)

216 (61.4)

0.044

 2. ILD

3 (0.9)

2 (0.6)

5 (1.5)

0.742

 3. Hypertension

134 (38.1)

112 (31.8)

246 (69.9)

0.367

 4. Hyperlipidemia

111 (31.5)

98 (27.8)

209 (59.3)

0.854

 5. CAD

77 (21.9)

54 (15.3)

131 (37.2)

0.078

 6. CHF

18 (5.1)

11 (3.1)

29 (8.2)

0.291

 7. CVA

21 (5.9)

21 (5.9)

42 (11.8)

0.708

 8. PAD

29 (8.3)

16 (4.5)

45 (12.8)

0.091

 9. DM

45 (12.8)

41 (11.6)

86 (24.4)

0.935

 10. Atrial fibrillation

31 (8.8)

19 (5.4)

50 (14.2)

0.155

 11. VTE

24 (6.8)

24 (6.8)

48 (13.6)

0.686

 12. CKD

23 (6.5)

12 (3.4)

35 (9.9)

0.104

 13. OSA

26 (7.4)

20 (5.7)

46 (13.1)

0.578

 14. GERD

80 (22.7)

63 (17.9)

143 (40.6)

0.365

 15. Anxiety

65 (18.5)

50 (14.2)

115 (32.7)

0.371

 16. Hypothyroidism

31 (8.8)

33 (9.3)

64 (18.1)

0.449

 17. Chronic liver dysfunction

8 (2.2)

7 (2)

15 (4.2)

0.960

 18. Co-existing cancer

19 (5.4)

10 (2.8)

29 (8.2)

0.201

Home O2 use

29 (8.3)

22 (6.2)

51 (14.5)

0.520

PFT performed:

175 (49.7)

161 (45.7)

336 (95.4)

0.191

 1. FEV1, % predicted

76.03 ± 18.97

76.68 ± 24.45

76.34 ± 21.76

0.781

 2. FVC, % predicted

85.77 ± 17.33

85.94 ± 19.04

85.85 ± 18.16

0.932

 3. Ratio FEV1/FVC

67.91 ± 11.09

67.57 ± 13.26

67.74 ± 12.17

0.796

 4. TLC, % predicted

106.42 ± 17.60

107.24 ± 22.49

106.83 ± 20.15

0.723

 5. RV, % predicted

138.53 ± 40.82

143.71 ± 22.49

141.13 ± 51.41

0.384

 6. DLCO, % predicted

66.29 ± 20.55

71.84 ± 23.01

69.06 ± 21.95

0.023

Mortality (dead)

32 (9.1)

8 (2.2)

40 (11.3)

< 0.001

  1. Bold italics p-value suggest statistical significant p-value (alpha < 0.05)
  2. CAD coronary artery disease, CHF congestive heart failure, CKD chronic kidney disease, COPD chronic obstructive lung disease, CVA cerebrovascular accident, DLCO diffusion capacity for carbon monoxide, DM diabetes mellitus, FEV1 forced expiratory volume in one second, FVC forced vital capacity, GERD gastro-esophageal reflux disease, ILA interstitial lung abnormalities, ILD interstitial lung disease, OSA obstructive sleep apnea, PAD peripheral arterial disease, RV residual volume, TLC total lung capacity, VTE venous thromboembolism
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BMC Pulmonary Medicine

ISSN: 1471-2466

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