Diagnostic value of miRNA expression and right ventricular echocardiographic functional parameters for chronic thromboembolic pulmonary hypertension with right ventricular dysfunction and injury

Table 2 Clinical and hemodynamic characteristics of CTEPH patients in the study group

Characteristics	Patients, n = 8
Clinical characteristics
Age, years	61.0 ± 6.8
BMI, kg/m²	22.6 ± 2.3
Female/male, n	4/4
Family history of blood clots (Y/N)	0/8
Long-term inactivity (Y/N)	0/8
Pleural effusion (Y/N)	0/8
Other risk factors for CTEPH	5/3
Smoking (Y/N)	4/4
WHO FC, I/II/III/IV	1/6/1/0
6MWD, m	391 ± 106
Hemodynamic parameters
mPAP, mmHg	54.13 ± 12.43
PVR, dyn.sec/cm⁵	943.7 ± 237.5
CI, l/min/m²	2.33 ± 0.41
CO, L/min	3.74 ± 0.85
SvO2, %	52.00 ± 8.16
Laboratory findings
NT-proBNP, pg/ml	1190.2 ± 1448.8
D-dimer, µg/l	240.45(148.14)
CRP, mg/dl	0.185(0.330)
Plasminogen, %	81.37 ± 8.64
NSE, ng/ml	22.05 ± 3.86
PC, %	53.53 ± 20.64
PS, %	60.36 ± 32.96
AT, %	79.24 ± 10.34

BMI body mass index, Y/N yes/no, CTEPH chronic thromboembolic pulmonary hypertension, WHO FC World Health Organization functional class, 6MWD six-minute walk distance, mPAP mean pulmonary artery pressure, PVR pulmonary vascular resistance, CI cardiac index, CO cardiac output, NT-proBNP N-terminal pro b-type natriuretic peptide, CRP C-reactive protein, NSE neuron-specific enolase, PC protein C, PS protein S, AT antithrombin

ISSN: 1471-2466