Fig. 5From: Probiotic in the prevention of ventilator-associated pneumonia in critically ill patients: evidence from meta-analysis and trial sequential analysis of randomized clinical trialsTrial sequential analysis for effects of probiotics on VAP incidence in adult patients. The required information size of 6077 was calculated based on the VAP incidence of 20.69, 25.27% in the probiotic and placebo group, respectively (α = 5%, β = 20%, I2 = 56.40%)Back to article page