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Table 2 Comparison of biopsy specimens, safety, diagnosis, and prognosis between the patients underwent TBLB and TBLC

From: Transbronchial lung biopsy versus transbronchial lung cryobiopsy in critically ill patients with undiagnosed acute hypoxemic respiratory failure: a comparative study

 

TBLB (n = 45)

TBLC (n = 25)

p value

Specimen (Median, IQR)

   

Number

4 (2–6)

4 (3–5)

0.380

Length diameter, mm

1.0 (0.5–2.0)

5.3 (4.8–5.6)

 < 0.001

Short diameter, mm

0.5 (0.5–0.8)

3.7 (3.3–4.3)

 < 0.001

Artifacts (n, %)

   

Crash/atelectasis

25 (55.6)

0

 < 0.001

Traumatic bleeding

4 (8.9)

4 (16.0)

0.443

Non-alveolar tissue

8 (17.8)

0

0.044

Complications (n, %)

7 (15.6)

7 (28.0)

0.212

Moderate bleeding

0

7 (28.0)

 < 0.001

Severe bleeding

0

0

Pneumothorax

6 (13.3)

0

0.056

Others

1 (2.2)

0

1.000

ΔAPACHE II score ≥ 5 (n, %)

0

4 (16.0)

0.006

ΔSOFA score ≥ 3 (n, %)

1 (2.2)

4 (16.0)

0.032

Pathological diagnosis (n, %)

17 (37.8)

18 (72.0)

0.006

MDD diagnosis (n, %)

25 (55.6)

21 (84.0)

0.016

Treatment modifications (n, %)

26 (57.8)

21 (84.0)

0.025

28-day survival (n, %)

25 (55.6)

16 (64.0)

0.492

  1. APACHE II score, acute physiology and chronic health evaluation II score; SOFA score, sequential organ failure assessment score; MDD, Multidisciplinary discussion
  2. Bold for statistically significant (p value < 0.05)