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Table 5 Identifying asbestosis and FHP in pulmonary interstitial and parenchyma features on HRCT

From: High-resolution computed tomography features of asbestosis versus fibrotic hypersensitivity pneumonitis: an observational study

Characteristics

Sensitivity

Specificity

PPV

NPV

+ LR (95% CI)

− LR (95% CI)

Irregular and/or linear opacities

      

 Interlobular opacities

0.94

0

0.72

0

0.94 (0.91–0.97)

 Subpleural lines

0.27

0.88

0.86

0.31

2.26 (1.18–4.33)

0.83 (0.73–0.93)

 Subpleural dots

0.57

0.86

0.92

0.42

4.21 (2.34–7.58)

0.50 (0.42–0.60)

 Honeycombing

0.09

0.92

0.76

0.27

1.15 (0.48–2.77)

0.99 (0.91–1.07)

Inhomogeneous attenuation

      

 Mosaic attenuation

0.22

0.80

0.75

0.27

1.10 (0.65–1.83)

0.98 (0.85–1.12)

 Three-density pattern

0.15

0.82

0.70

0.26

0.87 (0.48–1.56)

1.03 (0.91–1.16)

 Ground glass opacity

0.60

0.07

0.64

0.06

0.65 (0.57–0.73)

5.88 (2.48–13.93)

  1. The PPV represents the patients who were diagnosed as asbestosis
  2. HRCT high-resolution computed tomography, PPV positive predictive value, NPV negative predictive value, + LR positive likelihood ratio, − LR negative likelihood ratio, CI confidence interval