Table 1 Baseline cohort characteristics of IPF-CS patients with and without left-sided HF
|  | IPF-CS -no HF (N = 20,309) n | (%) | IPF-CS + HF (N = 5032) n | (%) |
|---|---|---|---|---|
Age (years) | Â | Â | Â | Â |
40–49 | 404 | (2.0) | 35 | (0.7) |
50–59 | 1541 | (7.6) | 145 | (2.9) |
60–69 | 4367 | (21.5) | 672 | (13.4) |
70–79 | 7536 | (37.1) | 1869 | (37.1) |
80–89 | 5664 | (27.9) | 1976 | (39.3) |
90+ | 797 | (3.9) | 335 | (6.7) |
Sex | Â | Â | Â | Â |
Male | 12,001 | (59.1) | 3288 | (65.3) |
Female | 8308 | (40.9) | 1744 | (34.7) |
Ethnicity | Â | Â | Â | Â |
White | 16,601 | (81.7) | 4225 | (84.0) |
Asian | 882 | (4.3) | 216 | (4.3) |
Black | 209 | (1.0) | 51 | (1.0) |
Mixed | 41 | (0.2) | 11 | (0.2) |
Other | 478 | (2.35) | 74 | (1.5) |
Unknown | 2098 | (10.3) | 455 | (9.0) |
IMD | Â | Â | Â | Â |
1 (least deprived) | 4523 | (22.3) | 988 | (19.6) |
2 | 4348 | (21.4) | 1095 | (21.8) |
3 | 924 | (19.3) | 951 | (18.9) |
4 | 3729 | (18.4) | 1002 | (20.0) |
5 (most deprived) | 3762 | (18.5) | 989 | (19.7) |
Unknown | 23 | (0.1) | 7 | (0.1) |
BMI | Â | Â | Â | Â |
< 18.5 | 690 | (3.4) | 113 | (2.2) |
18.5–24.9 | 5585 | (27.5) | 1241 | (24.7) |
25.0–29.9 | 6202 | (30.5) | 1652 | (32.8) |
> 30 | 4248 | (20.9) | 1329 | (26.4) |
Unknown | 3584 | (17.6) | 697 | (13.9) |
Smoking | Â | Â | Â | Â |
Non-smoker | 3095 | (15.2) | 661 | (13.1) |
Ex-smoker | 14,123 | (69.5) | 3763 | (74.8) |
Current smoker | 3047 | (15.0) | 600 | (11.9) |
Unknown | 44 | (0.2) | 8 | (0.2) |
Alcohol | Â | Â | Â | Â |
Non-drinker | 2714 | (13.4) | 708 | (14.1) |
Ex-drinker | 252 | (1.2) | 80 | (1.6) |
Current drinker | 11,467 | (56.5) | 3077 | (61.1) |
Unknown | 5876 | (28.9) | 1167 | (23.2) |
Comorbidities | Â | Â | Â | Â |
Hypertension | 9709 | (47.8) | 3027 | (60.2) |
COPD | 4501 | (22.2) | 1367 | (27.2) |
IHD | 4297 | (21.2) | 2496 | (49.6) |
CKD | 4518 | (22.2) | 1980 | (39.3) |
Type II diabetes | 4152 | (20.4) | 1450 | (28.9) |
Anaemia | 3359 | (16.5) | 1193 | (23.7) |
Atrial fibrillation | 1964 | (9.7) | 1619 | (32.2) |
Stroke | 2120 | (10.4) | 769 | (15.3) |
Valvular heart disease | 1188 | (5.8) | 963 | (19.1) |
Peripheral arterial disease | 1064 | (5.2) | 493 | (9.8) |
Medications | Â | Â | Â | Â |
Statin | 9501 | (46.8) | 3234 | (64.3) |
Antiplatelets | 6989 | (34.4) | 2604 | (51.7) |
ACE inhibitors | 4913 | (24.2) | 2255 | (44.8) |
Calcium-channel blockers | 5154 | (25.4) | 1417 | (28.2) |
Beta-blockers | 4332 | (21.3) | 2491 | (49.5) |
Diuretics | 2905 | (14.3) | 955 | (19.0) |
ARBs | 3020 | (14.9) | 1218 | (24.2) |
Anticoagulants | 1857 | (9.1) | 1387 | (27.6) |
Short-acting nitrates | 1426 | (7.0) | 796 | (15.8) |
Long-acting nitrates | 1132 | (5.6) | 762 | (15.1) |
Digoxin | 592 | (2.9) | 588 | (11.7) |
MRAs | 364 | (1.8) | 725 | (14.4) |
Amiodarone | 159 | (0.8) | 213 | (4.2) |
Ivabradine | 58 | (0.3) | 76 | (1.5) |
ARNI | 0 | Â | 19 | (0.4) |