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Table 1 Univariate analysis for the association between risk factors and massive hemoptysis in patients with bronchiectasis

From: A retrospective analysis of risk factors for massive hemoptysis in patients with bronchiectasis

 

Massive hemoptysis

P2)

OR (95% CI)

P (OR)

Total (n = 379)

No (n = 318)

Yes (n = 61)

Gender

   

0.020*

  

 Male

197 (51.98)

157 (79.70)

40 (20.30)

 

Ref

 

 Female

182 (48.02)

161 (88.46)

21 (11.54)

 

0.512 (0.289, 0.907)

0.022*

Age (years)

   

0.915

  

 < 40

23 (6.07)

19 (82.61)

4 (17.39)

 

Ref

 

 (40,50)

61 (16.09)

52 (85.25)

9 (14.75)

 

0.822 (0.226, 2.986)

0.766

 (50,60)

93 (24.54)

79 (84.95)

14 (15.05)

 

0.842 (0.249, 2.848)

0.782

 (60,70)

108 (28.50)

92 (85.19)

16 (14.81)

 

0.826 (0.248, 2.748)

0.755

 ≥ 70

94 (24.80)

76 (80.85)

18 (19.15)

 

1.125 (0.341, 3.714)

0.847

Smoking

   

0.073

  

 Never

277 (73.09)

238 (85.92)

39 (14.08)

 

Ref

 

 Current

72 (19.00)

54 (75.00)

18 (25.00)

 

2.034 (1.081, 3.826)

0.028*

 Former

30 (7.92)

26 (86.67)

4 (13.33)

 

0.939 (0.311, 2.837)

0.911

Course (years)

   

0.075

  

 ≤ 1

124 (32.72)

97 (78.23)

27 (21.77)

 

Ref

 

 (1,5]

74 (19.53)

68 (91.89)

6 (8.11)

 

0.317 (0.124, 0.809)

0.016*

 (5,10]

74 (19.53)

61 (82.43)

13 (17.57)

 

0.766 (0.367, 1.597)

0.476

 > 10

107 (28.23)

92 (85.98)

15 (14.02)

 

0.586 (0.293, 1.171)

0.130

PTMH

   

0.242

  

 No

357 (94.20)

302 (84.59)

55 (15.41)

 

Ref

 

 Yes

22 (5.80)

16 (72.73)

6 (27.27)

 

2.059 (0.772, 5.493)

0.149

Hypertension

   

0.334

  

 No

320 (84.43)

271 (84.69)

49 (15.31)

 

Ref

 

 Yes

59 (15.57)

47 (79.66)

12 (20.34)

 

1.412 (0.699, 2.853)

0.336

Diabetes

   

0.154

  

 No

359 (94.72)

304 (84.68)

55 (15.32)

 

Ref

 

 Yes

20 (5.28)

14 (70.00)

6 (30.00)

 

2.369 (0.873, 6.430)

0.091

COPD

   

0.658

  

 No

306 (80.74)

258 (84.31)

48 (15.69)

 

Ref

 

 Yes

73 (19.26)

60 (82.19)

13 (17.81)

 

1.165 (0.594, 2.285)

0.658

Asprin

   

1.000

  

 No

366 (96.57)

307 (83.88)

59 (16.12)

 

Ref

 

 Yes

13 (3.43)

11 (84.62)

2 (15.38)

 

0.946 (0.204, 4.378)

0.943

Anticoagulation

   

0.410

  

 No

376 (99.21)

316 (84.04)

60 (15.96)

 

Ref

 

 Yes

3 (0.79)

2 (66.67)

1 (33.33)

 

2.633 (0.235, 29.504)

0.432

Invasive pulmonary aspergillosis

   

0.334

  

 No

370 (97.63)

312 (84.32)

58 (15.68)

 

Ref

 

 Yes

9 (2.37)

6 (66.67)

3 (33.33)

 

2.690 (0.654, 11.060)

0.170

Pneumonia

   

0.658

  

 No

306 (80.74)

258 (84.31)

48 (15.69)

 

Ref

 

 Yes

73 (19.26)

60 (82.19)

13 (17.81)

 

1.165 (0.594, 2.285)

0.658

PLT (× 109/L)

   

0.698

  

 Normal

317 (83.64)

268 (84.54)

49 (15.46)

 

Ref

 

 Low

44 (11.61)

35 (79.55)

9 (20.45)

 

1.406 (0.636, 3.109)

0.399

 High

18 (4.75)

15 (83.33)

3 (16.67)

 

1.094 (0.305, 3.920)

0.890

D-dimer (mg/l)

   

0.620

  

 Normal

276 (72.82)

230 (83.33)

46 (16.67)

 

Ref

 

 High

103 (27.18)

88 (85.44)

15 (14.56)

 

0.852 (0.453, 1.604)

0.620

Lobes

   

0.012*

  

 1

128 (33.77)

113 (88.28)

15 (11.72)

a

Ref

 

 2

87 (22.96)

63 (72.41)

24 (27.59)

b

2.870 (1.404, 5.866)

0.004**

 3

59 (15.57)

49 (83.05)

10 (16.95)

ab

1.537 (0.646, 3.661)

0.331

 4

31 (8.18)

29 (93.55)

2 (6.45)

ab

0.520 (0.112, 2.401)

0.402

 5

74 (19.53)

64 (86.49)

10 (13.51)

ab

1.177 (0.500, 2.773)

0.709

Left upper lobe

   

0.732

  

 No

185 (48.81)

154 (83.24)

31 (16.76)

 

Ref

 

 Yes

194 (51.19)

164 (84.54)

30 (15.46)

 

0.909 (0.525, 1.572)

0.732

Left lower lobe

   

0.029*

  

 No

128 (33.77)

100 (78.12)

28 (21.88)

 

Ref

 

 Yes

251 (66.23)

218 (86.85)

33 (13.15)

 

0.541 (0.310, 0.943)

0.030*

Right upper lobe

   

0.137

  

 No

237 (62.53)

204 (86.08)

33 (13.92)

 

Ref

 

 Yes

142 (37.47)

114 (80.28)

28 (19.72)

 

1.518 (0.873, 2.640)

0.139

Right middle lobe

   

0.595

  

 No

187 (49.34)

155 (82.89)

32 (17.11)

 

Ref

 

 Yes

192 (50.66)

163 (84.90)

29 (15.10)

 

0.862 (0.498, 1.491)

0.595

Right lower lobe

   

0.801

  

 No

192 (50.66)

162 (84.38)

30 (15.62)

 

Ref

 

 Yes

187 (49.34)

156 (83.42)

31 (16.58)

 

1.073 (0.620, 1.856)

0.801

  1. PTMH previous times of massive hemoptysis, COPD chronic obstructive pulmonary disease, PLT platelet
  2. *P < 0.05; **P < 0.01; ***P < 0.001; a,b: multiple comparisons were statistically significant; ab: multiple comparisons were not significant