Fig. 3

Hierarchical summary receiver operating characteristic (HSROC) plots demonstrate summary operating point (red square), 95% confidence interval (yellow dash line) and HSROC curve (green solid line) of A QuantiFERON-TB Gold In-Tube and B T-SPOT.TB for diagnosis of smear-negative pulmonary tuberculosis. Open circles represent individual study included in the meta-analysis, with circle size representing the sample size in each study