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Table 4 Mathematical equations to predict CPAP level for patients with OSA in literatures

From: A predictive model for optimal continuous positive airway pressure in the treatment of pure moderate to severe obstructive sleep apnea in China

Study group, year

Country

Number of patients, Development (D)/Validation (V)

Mathematical equation

Ebben MR [8]

USA

Oronasal mask

D = 66 V = 66

Nasal mask

D = 100 V = 100

Oronasal mask 0.03 × AHI-0.130 × minSpO2 + 19.732

Nasal mask 0.017 × AHI-0.092 × minSpO2 + 0.225 × NC + 5.534

SaiphoklangN [16]

Thailand

D = 180 V = 0

4.614 + 0.173 × NC + 0.067 × BMI + 0.030 × RDI-0.076 × minSpO2

Wu MF [23]

China

D = 57 V = 30

6.380 + 0.033 × AHI-0.068 × minSpO2 + 0.171 × BMI

Lee GH [24]

Korea

D = 178 V = 178

6.656 + 0.156 × BMI-0.071 × minSpO2 + 0.041 × RDI + 0.094ESS

Schiza SE [25]

Greece

D = 1111 V = 0

Men 5.16 + 0.003 × smoking in pack years + 0.054 × BMI + 

0.016 × AHI-0.403

Women 5.16 + 0.003 × smoking in pack years + 0.054 × BMI + 

0.016 × AHI-0.806

Liu JH [26]

China

D = 134 V = 0

− 0.7656 + 1.3148 × Sex + 0.2147 × Neck + 0.0175 × LAT + 0.0291 × AHI

Xia SY [27]

China

D = 139 V = 0

2.878 + 0.035 × AHI + 0.035 × LAT + 0.034 × WC

Loredo JS [29]

USA

D = 76 V = 0

30.8 + RDI × 0.03-minSpO2 × 0.05-meanSpO2 × 0.2

  1. AHI, apnea hypopnea index; minSpO2, minimum percutaneous oxygen saturation; NC, neck circumference; BMI, body mass index; RDI, Respiratory disturbance index; ESS, Epworth Sleepiness Score; meanSpO2, mean percutaneous oxygen saturation; LAT, longest apnea time; WC, waist circumference