Fig. 1

Frequencies of invasion into surrounding tissue and internal low-density areas. The frequencies of invasion into surrounding tissue and internal low-density areas were significantly higher in patients with stage III/IV NSCLC harboring METex14 skipping than in those with stage I/II disease (a). This tendency was also observed in patients with adenocarcinoma (n = 10) (b). Additionally, the frequencies of invasion into surrounding tissue and internal low-density areas were higher in masses larger than 30 mm (c). *p < 0.05, Fisher’s exact test