Table 1 Patients’ characteristics
Variable | Adjuvant chemotherapy | Observation | p-value | Matched observation group | p-value |
|---|---|---|---|---|---|
Patients, n (%) | 30 (100) | 110 (100) | 30 (100) | ||
Age, years | < 0.001 | 0.8 | |||
Median | 76.2 | 79 | 76.7 | ||
Min.–Max. | 75–81 | 75–91 | 75–81 | ||
Gender, n (%) | 0.084 | 0.58 | |||
Male | 22 (73) | 59 (54) | 19 (63) | ||
Female | 8 (27) | 51 (46) | 11 (37) | ||
Smoking status, n (%) | 0.364 | 0.22 | |||
Never | 6 (20) | 32 (29) | 3 (10) | ||
Former | 20 (67) | 56 (51) | 18 (60) | ||
Current | 4 (13) | 22 (20) | 9 (30) | ||
CCI, n (%) | 0.46 | 0.434 | |||
0 | 7 (23) | 21 (19) | 5 (17) | ||
1 | 11(37) | 31 (28) | 8 (27) | ||
≥ 2 | 12 (40) | 58 (53) | 17 (56) | ||
Stage, n (%) | 0.001 | 1 | |||
II | 3 (10) | 48 (44) | 3 (10) | ||
III | 27 (90) | 62 (56) | 27 (90) | ||
T status, n (%) | 0.44 | 0.386 | |||
1 | 1 (3) | 2 (2) | 2 (7) | ||
2 | 11 (37) | 37 (34) | 7 (23) | ||
3 | 7 (23) | 43 (39) | 11 (37) | ||
4 | 11 (37) | 28 (25) | 10 (33) | ||
N status, n (%) | < 0.001 | 0.406 | |||
0 | 6 (20) | 43 (39) | 7 (23) | ||
1 | 8 (27) | 48 (44) | 12 (40) | ||
2 | 16 (53) | 19 (17) | 11 (37) | ||
PS ECOG, n (%) | 0.206 | 0.3 | |||
0 | 19 (63) | 53 (48) | 14 (47) | ||
1 | 11 (37) | 57 (52) | 16 (53) | ||
Histopathology, n (%) | 1 | 1 | |||
Squamous | 15 (50) | 55 (50) | 16 (53) | ||
Non-squamous | 15 (50) | 55 (50) | 14 (47) | ||
Type of surgery, n (%) | 0.568 | 0.67 | |||
Lobar resection | 23 (76) | 89 (81) | 22 (74) | ||
Sub-lobar resection | 5 (17) | 11 (10) | 4 (13) | ||
Pneumonectomy | 2 (7) | 10 (9) | 4 (13) |