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Table 1. Baseline characteristics of the train cohort comparing survived vs non-survived patients

From: Development and validation of a clinical risk model to predict the hospital mortality in ventilated patients with acute respiratory distress syndrome: a population-based study

 

Survivor (n=506)

Non-survivor (n=246)

P

Age, yr (median [IQR])

58.19 [46.64, 68.06]

64.25 [55.00, 76.92]

<0.001

BMI (median [IQR])

28.53 [24.10, 35.34]

27.64 [23.73, 33.53]

0.187

Gender(male)

284 (56.1%)

138 (56.1%)

>0.999

Comorbidity, n (%)

Asthma

28 (5.5)

10 (4.1)

0.493

CHF

126 (24.9)

71 (28.9)

0.284

AFIB

93 (18.4)

55 (22.4)

0.234

Renal diseases

37 (7.3)

29 (11.8)

0.058

Liver diseases

17 (3.4)

20 (8.1)

0.008

COPD

65 (12.8)

30 (12.2)

0.893

CAD

41 (8.1)

19 (7.7)

0.971

Diabetes

70 (13.8)

32 (13.0)

0.844

Hypertension

120 (23.7)

49 (19.9)

0.281

Stroke

27 (5.3)

16 (6.5)

0.631

Malignancy

53 (10.5)

39 (15.9)

0.046

Number of comorbidities, n (%)

  

0.297

0

179 (35.4)

66 (26.8)

 

1

139 (27.5)

76 (30.9)

 

2

93 (18.4)

49 (19.9)

 

3

50 (9.9)

35 (14.2)

 

4

28 (5.5)

13 (5.3)

 

5

13 (2.6)

4 (1.6)

 

6

3 (0.6)

2 (0.8)

 

7

1 (0.2)

1 (0.4)

 

Vasopressor usage

182 (36.0)

111 (45.1)

0.020

ARDS severity, n (%) *

  

0.003

Mild

60 (11.9)

28 (11.4)

 

Moderate

226 (44.7)

80 (32.5)

 

Severe

220 (43.5)

138 (56.1)

 

Subgroup of ARDS, n (%)

  

0.643

Direct (pulmonary) ARDS

325 (64.2)

153 (62.2)

 

Indirect (extrapulmonary) ARDS

181 (35.6)

93 (37.8)

 

Severity score

SAPS II (median [IQR])

41.00 [32.00, 50.00]

49.00 [39.00, 60.00]

<0.001

SOFA (median [IQR])

7.00 [4.00, 9.00]

8.00 [5.00, 11.00]

<0.001

OASIS (median [IQR])

36.00 [31.00, 42.00]

40.00 [34.00, 45.00]

<0.001

APACHE IV (median [IQR])

72.00 [53.00, 91.00]

91.50 [70.75, 114.75]

<0.001

APPS (median [IQR])

6.00 [5.00, 7.00]

6.00 [5.00, 7.00]

<0.001

  1. BMI body mass index, CHF chronic heart failure, AFIB atrial fibrillation, COPD chronic obstructive pulmonary disease, CAD coronary artery disease,ARDS Acute Respiratory Distress Syndromes, SAPS II Simplified Acute Physiology Score II, SOFA Sequential Organ Failure Assessment, OASIS Oxford Acute Severity of Illness Score, APACHE IV Acute Physiology and Chronic Health Evaluation IV, APPS Age, PaO2/FiO2, and Plateau Pressure Score
  2. *ARDS severity: Mild (200 mmHg < PaO2/FiO2 ≤300 mmHg); Moderate (100 < PaO2/FiO2 ≤200 mmHg); Severe (PaO2/FiO2 ≤100 mmHg)