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Table 3 PAH-targeted therapy before and after RHC in WHO group 1 PH, WHO group 2 PH, and hyperdynamic PH

From: Diversity of hemodynamic types in connective tissue disease associated pulmonary hypertension: more than a subgroup of pulmonary arterial hypertension

 

WHO group 1 PH n = 138

WHO group 2 PH n = 33

Hyperdynamic PH n = 31

p value

PAH-targeted therapy before RHC, No. (%)

70 (50.7)

22 (66.7)

20 (64.5)

0.151

PAH-targeted therapy after RHC, No. (%)

103 (83.3)

20 (60.6)

11 (35.5)

 < 0.01

 Monotherapy, No. (%)

89 (64.5)

13 (39.4)

8 (25.8)

 

 Combined therapy, No. (%)

25 (18.1)

7 (21.2)

3 (9.7)

 

 ERA, No. (%)

60 (43.8)

12 (37.5)

7 (22.6)

 

 PDE-I, No. (%)

79 (57.7)

14 (43.8)

7 (22.6)

 

 PGs, No. (%)

3 (2.2)

0 (0)

0 (0)

 

 GCA, No. (%)

0 (0)

0 (0)

1 (3.2)

 
  1. p-values <0.05 is shown in bold, which means statistically significant
  2. PAH Pulmonary arterial hypertension, RHC Right heart catheterization, WHO World Health Organization, PH Pulmonary hypertension, ERA Endothelin receptor antagonist, PDE-I Phosphodiesterase inhibitor, PGs Prostaglandin analogs, GCA Guanylate cyclase agonist