Table 1 Patient characteristics
Characteristics | Cases (n, %) |
|---|---|
Age [median (range), years] | 52(12–82) |
Gender | Â |
 Male | 362(47.0%) |
 Female | 408(53.0%) |
Smokers | 152(19.7%) |
Primary site | Â |
 Lung | 598(77.7%) |
 Salivary glands | 115(14.9%) |
 GI tract | 19(2.5%) |
 others | 38(4.9%) |
Stage at diagnosis | Â |
 I | 118(15.3%) |
 II | 133(13.3%) |
 III | 252(32.7%) |
 IV | 258(33.5%) |
 NA | 9(1.2%) |
Initial treatment | Â |
 Surgery | 522(67.8%) |
 Chemotherapy | 311(40.4%) |
 Radiotherapy | 100(13.0%) |
CK | Â |
 Positive | 414(53.8%) |
 Negative | 6(0.8%) |
 NA | 350(45.4%) |
p63 | Â |
 Positive | 524(68.1%) |
 Negative | 17(2.2%) |
 NA | 229(29.7%) |
CK5/6 | Â |
 Positive | 555(72.1%) |
 Negative | 18(2.4%) |
 NA | 197(25.6%) |
EBER | Â |
 Positive | 668(98.4%) |
 Negative | 11(1.6%) |
 NA | 91 |
EBV-DNA copy | Â |
 ≥ 103 IU/mL | 174(50.6%) |
 < 103 IU/mL | 53(15.4%) |
 0 | 117(34.0%) |
 NA | 426 |
Gene sequencing | Â |
 EGFR mutation | 10(3.3%) |
 ALK arrangement | 3(1.0%) |
 TP53 mutation | 7(2.3%) |
 NOTCH mutation | 2(0.7%) |
 No driver gene mutation detected | 283(92.8%) |
 NA | 465 |