Table 2 Univariate and multivariate analysis of Cox-proportional hazards model for the risk of 30-day mortality
Univariate (HR, 95% CI) | P value | Multivariate (HR, 95% CI) | VIF | P value | |
|---|---|---|---|---|---|
Age | 1.057 (1.030, 1.085) | < 0.001 | 1.066 (1.037, 1.095) | 1.3 | < 0.001 |
Male | 0.973 (0.622, 1.521) | 0.904 | / | – | – |
Laboratory tests | |||||
WBC count | 1.025 (0.999, 1.052) | 0.063 | / | – | – |
Neutrophil count | 1.034 (1.004, 1.065) | 0.026 | / | – | / |
Lymphocyte count | 0.886 (0.709, 1.107) | 0.287 | / | – | – |
Platelet count | 1.000 (0.998, 1.002) | 0.779 | – | – | – |
Hemoglobin | 0.930 (0.829, 1.043) | 0.213 | – | – | – |
Serum albumin | 0.547 (0.379, 0.787) | 0.001 | – | – | – |
Serum sodium | 0.995 (0.954, 1.037) | 0.799 | – | – | – |
Serum potassium | 0.772 (0.580, 1.027) | 0.076 | – | – | – |
Serum calcium | 1.257 (0.056, 28.164) | 0.885 | – | – | – |
pH | 0.474 (0.059, 3.820) | 0.483 | – | – | – |
pO2 | 0.998 (0.996, 1.000) | 0.079 | 0.997 (0.995, 0.999) | 1.1 | 0.009 |
pCO2 | 1.000 (0.990, 1.011) | 0.957 | – | – | – |
Bicarbonate | 1.010 (0.975, 1.045) | 0.588 | – | – | – |
ALT | 0.999 (0.997, 1.001) | 0.409 | – | – | – |
AST | 0.999 (0.997, 1.001) | 0.484 | – | – | – |
Serum creatinine | 1.058 (0.881, 1.270) | 0.547 | – | – | – |
BUN | 1.006 (0.997, 1.015) | 0.192 | – | – | – |
Mean vital signs | |||||
Temperature | 0.934 (0.641, 1.361) | 0.723 | – | – | – |
MAP | 0.984 (0.962, 1.007) | 0.175 | – | – | – |
Heart rate | 1.012 (0.997, 1.028) | 0.122 | – | – | – |
Respiratory rate | 1.018 (0.964, 1.075) | 0.524 | – | – | – |
Comorbidities | |||||
Hypertension | 0.635 (0.402, 1.004) | 0.052 | – | – | – |
DM | 0.710 (0.581, 1.025) | 0.056 | – | – | – |
CHD | 1.383 (0.697, 1.745) | 0.225 | – | – | – |
CKD | 0.564 (0.271, 1.173) | 0.125 | – | – | – |
Malignancy | 1.190 (0.731, 1.939) | 0.484 | – | – | – |
Inflammatory indicators | |||||
NLR | 1.009 (1.003, 1.016) | 0.006 | 1.006 (1.001, 1.013) | 1.4 | 0.048 |
PLR | 1.000 (1.000, 1.001) | 0.108 | – | – | – |
PNI | 0.941 (0.908, 0.975) | < 0.001 | 0.958 (0.923, 0.994) | 1.0 | 0.024 |
Scoring system | |||||
SAPSII | 1.037 (1.020, 1.054) | < 0.001 | – | – | – |
SOFA | 1.099 (1.020, 1.184) | 0.013 | – | – | – |
Treatment | |||||
MV | 2.602 (1.339, 5.057) | 0.005 | 2.516 (1.265, 5.005) | 1.2 | 0.008 |
Vasopressor | 2.206 (1.408, 3.455) | < 0.001 | 2.042 (1.267, 3.292) | 1.4 | 0.003 |