Table 3 Sensitivity and specificity of KL-6 and geographic appearance for the diagnosis of DAD
Sensitivity, % (95% CI) | Specificity, % (95% CI) | Positive likelihood ratio (95% CI) | Negative likelihood ratio (95% CI) | |
|---|---|---|---|---|
KL-6 > 500 U/mL | 61 (36–83) | 89 (52–100) | 5.5 (0.8–36.2) | 0.4 (0.2–0.8) |
Geographic appearance | 89 (65–99) | 56 (21–86) | 2.0 (0.9–4.2) | 0.2 (0.05–0.8) |
Geographic appearance and | ||||
KL-6 > 500 U/mL | 56 (31–79) | 100 (56–100) | NA | 0.4 (0.3–0.7) |