Table 2 Demographic and clinical characteristics of female patients with NTM-LD
Variables | All | Disease severity | p Valuea | |
|---|---|---|---|---|
Mild | Severe | |||
(n = 81) | (n = 40) | (n = 41) | ||
Age (years) | 70.8 ± 8.6 | 69.0 ± 7.0 | 72.6 ± 9.6 | 0.060 |
Smoking history (pack·year) | 0.2 ± 1.2 | 0.3 ± 1.1 | 0.2 ± 1.2 | 0.762 |
Duration of NTM-LD (month) | 72.3 ± 56.0 | 51.8 ± 41.9 | 92.9 ± 61.1 | 0.053 |
Comorbidity | ||||
Malignancy (includes lung cancer) | 17 (21.0) | 9 (22.5) | 8 (19.5) | 0.790 |
Respiratory diseases | 5 (6.2) | 2 (5.0) | 3 (7.3) | 1.000 |
Diabetes mellitus | 4 (4.9) | 0 (0) | 4 (9.8) | 0.116 |
Cardiac diseases | 8 (9.9) | 4 (10.0) | 4 (9.8) | 1.000 |
Kidney diseases | 2 (2.5) | 0 (0) | 2 (4.9) | 0.494 |
Liver diseases | 4 (4.9) | 3 (7.5) | 1 (2.4) | 0.359 |
Radiological findingsb | ||||
NB | 60 (74.1) | 36 (90.0) | 24 (58.5) | 0.040 |
CavitaryNB | 18 (22.2) | 4 (10.0) | 14 (34.1) | |
FC | 3 (3.7) | 0 (0) | 3 (7.3) | |
With cavity | 21 (25.9) | 4 (10.0) | 17 (41.5) | 0.002 |
NTM species | ||||
M. avium | 51 (63.0) | 28 (70.0) | 23 (56.1) | 0.252 |
M. intracellulare | 28 (34.6) | 11 (27.5) | 17 (41.5) | 0.244 |
M. kansasii | 1 (1.2) | 1 (2.5) | 0 (0) | 0.494 |
M. abscessus | 7 (8.6) | 2 (5.0) | 5 (12.2) | 0.432 |
Antibiotic treatmentsb | ||||
Observation | 17 (21.0) | 14 (35.0) | 3 (7.3) | 0.009 |
One drug | 7 (8.6) | 3 (7.5) | 4 (9.8) | |
Two or more drugs | 57 (70.4) | 23 (57.5) | 34 (82.9) | |
Respiratory muscle strength | ||||
PEmax (cmH2O)c | 53.5 ± 23.9 | 62.8 ± 24.1 | 44.2 ± 20.1 | 0.001 |
PImax (cmH2O)d | 32.2 ± 13.5 | 37.1 ± 14.9 | 27.2 ± 9.8 | 0.001 |
Blood biochemistry | ||||
CRP (mg/dL) | 0.31 ± 0.73 | 0.18 ± 0.40 | 0.43 ± 0.94 | 0.119 |