Fig. 6

HMGB2 was correlated with cell cycle and proliferation in LUAD samples. A Correlations between the functional states and HMGB2 expression in patient 3 (LUAD) at the single-cell level. B Correlations between the functional states and HMGB2 expression in patient 4 (LUAD) at the single-cell level. C, D GSEA for HMGB2 using the data from the TCGA-LUAD dataset. C Cell cycle and D DNA replication pathways were enriched in the high expression group. E and F GSEA for HMGB2 using the data from the GSE10072 dataset. E Cell cycle and F DNA replication pathways were enriched in the high expression group