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Table 2 The risk factors for in-hospital mortality using univariate logistic regression analysis among elderly SCAP patients with CVD

From: Clinical profile analysis and nomogram for predicting in-hospital mortality among elderly severe community-acquired pneumonia patients with comorbid cardiovascular disease: a retrospective cohort study

Variables

Survival (n = 193)

Dead (n = 220)

OR (95%CI)

P value

Age (year)

    

 < 76

111 (57.5)

89 (40.5)

Ref

 

 ≥ 76

82 (42.5)

131 (59.5)

1.992 (1.346–2.950)

< 0.001

Sex

    

 Female

70 (36.3)

80 (36.4)

Ref

 

 Male

123 (63.7)

140 (63.6)

0.996 (0.666–1.489)

0.984

The use of vasopressor

    

 No

86 (44.6)

34 (15.5)

Ref

 

 Yes

107 (55.4)

186 (84.5)

4.397 (2.768–6.985)

< 0.001

Number of comorbidities

    

 0

63 (32.6)

25 (11.4)

Ref

 

 1

49 (25.4)

57 (25.9)

2.931 (1.608–5.343)

< 0.001

 ≥ 2

81 (42.0)

138 (62.7)

4.293 (2.506–7.356)

< 0.001

MACE

    

 No

166 (86.0)

172 (78.2)

Ref

 

 Yes

27 (14.0)

48 (21.8)

1.716 (1.023–2.879)

0.041

PaO2/FiO2

    

 ≥ 200

89 (46.1)

72 (32.7)

Ref

 

 < 200

104 (53.9)

148 (67.3)

1.759 (1.180–2.622)

0.006

Respiratory rate (breath/min)

    

 10–19

109 (56.5)

100 (45.5)

Ref

 

 ≥ 20

84 (43.5)

120 (54.5)

1.557 (1.055–2.298)

0.026

Heart rate (beat/min)

    

 < 100

120 (62.2)

109 (49.5)

Ref

 

 ≥ 100

73 (37.8)

111 (50.5)

1.674 (1.130–2.480)

0.010

Systolic blood pressure (mmHg)

    

 90–139

107 (55.4)

135 (61.4)

Ref

 

 < 90

15 (7.8)

23 (10.4)

1.215 (0.605–2.443)

0.584

 ≥ 140

71 (36.8)

62 (28.2)

0.692 (0.453–1.058)

0.090

Diastolic blood pressure (mmHg)

    

 60–89

123 (63.7)

132 (60)

Ref

 

 < 60

43 (22.3)

66 (30)

1.430 (0.907–2.256)

0.124

 ≥ 90

27 (14.0)

22 (10)

0.759 (0.411–1.403)

0.379

Temperature (°C)

    

 < 36.1

28 (14.5)

48 (21.8)

Ref

 

 ≥ 36.1

165 (85.5)

172 (78.2)

0.608 (0.364–1.015)

0.057

Albumin (g/L)

    

 ≥ 35

80 (41.5)

49 (22.3)

Ref

 

 < 35

113 (58.5)

171 (77.7)

2.471 (1.611–3.789)

< 0.001

A/G

    

 ≥ 1.5

61 (31.6)

54 (24.5)

Ref

 

 < 1.5

132 (68.4)

166 (75.5)

1.421 (0.923–2.188)

0.111

Total bilirubin (µmol/L)

    

 < 17

144 (74.6)

169 (76.8)

Ref

 

 ≥ 17

49 (25.4)

51 (23.2)

0.887 (0.565–1.392)

0.602

Direct bilirubin (µmol/L)

    

 < 6.8

131 (67.9)

132 (60)

Ref

 

 ≥ 6.8

62 (32.1)

88 (40)

1.409 (0.939–2.112)

0.097

ALT (IU/L)

    

 < 40

153 (79.3)

159 (72.3)

Ref

 

 ≥ 40

40 (20.7)

61 (27.7)

1.467 (0.930–2.316)

0.100

AST (IU/L)

    

 < 36

132 (68.4)

119 (54.1)

Ref

 

 ≥ 36

61 (31.6)

101 (45.9)

1.837 (1.227–2.748)

0.003

White blood cell (× 109/L)

    

 < 10

103 (53.4)

102 (46.4)

Ref

 

 ≥ 10

90 (46.6)

118 (53.6)

1.324 (0.899–1.951)

0.156

Monocyte (× 109/L)

    

 ≥ 0.8

30 (15.5)

21(9.5)

Ref

 

 < 0.2

25 (13.0)

53 (24.2)

3.029 (1.455–6.303)

0.003

 0.2–0.49

78 (40.4)

87 (39.5)

1.593 (0.844–3.010)

0.151

 0.5–0.79

60 (31.1)

59 (26.8)

1.405 (0.724–2.727)

0.315

Hemoglobin (g/L)

    

 ≥ 90

154 (79.8)

153 (69.5)

Ref

 

 < 90

39 (20.2)

67 (30.5)

1.729 (1.098–2.722)

0.018

Platelet (× 109/L)

    

 ≥ 100

161 (83.4)

140 (63.6)

Ref

 

 < 100

32 (16.6)

80 (36.4)

2.875 (1.800–4.592)

< 0.001

APTT (s)

    

 < 37

142 (73.6)

126 (57.3)

Ref

 

 ≥ 37

51 (26.4)

94 (42.7)

2.077 (1.369–3.151)

0.001

PT (s)

    

 < 13

112 (58.0)

88 (40)

Ref

 

 ≥ 13

81 (42.0)

132 (60)

2.074 (1.400–3.073)

< 0.001

Fibrinogen (g/L)

    

 < 2

24 (12.4)

29 (13.2)

Ref

 

 ≥ 2

169 (87.6)

191 (86.8)

0.935 (0.524–1.669)

0.821

D-dimer (mg/L)

    

 < 4

81 (42.0)

98 (44.5)

Ref

 

 ≥ 4

112 (58.0)

122 (55.5)

0.900 (0.609–1.330)

0.598

Creatinine (µmol/L)

    

 < 100

150 (77.7)

135 (61.4)

Ref

 

 ≥ 100

43 (22.3)

85 (38.6)

2.196 (1.423–3.391)

< 0.001

BUN (mg/dL)

    

 < 10

148 (76.7)

115 (52.3)

Ref

 

 ≥ 10

45 (23.3)

105 (47.7)

3.003 (1.962–4.597)

< 0.001

Troponin T (ng/mL)

    

 < 100

169 (87.6)

161 (73.2)

Ref

 

 ≥ 100

24 (12.4)

59 (26.8)

2.580 (1.532–4.346)

< 0.001

BNP (pg/mL)

    

 < 3364.5

160 (82.9)

128 (58.2)

Ref

 

 ≥ 3364.5

33 (17.1)

92 (41.8)

3.485 (2.199–5.524)

< 0.001

Glucose (mmol/L)

    

 < 7.4

116 (60.1)

94 (42.7)

Ref

 

 ≥ 7.4

77 (39.9)

126 (57.3)

2.019 (1.363–2.991)

< 0.001

Lactate (mmol/L)

    

 < 2.1

152 (78.8)

149 (67.7)

Ref

 

 ≥ 2.1

41 (21.2)

71 (32.3)

1.767 (1.131–2.759)

0.012

PCT (ng/mL)

    

 < 0.5

134 (69.4)

105 (47.7)

Ref

 

 0.5–1.9

38 (19.7)

59 (26.8)

1.981 (1.225–3.206)

0.005

 ≥ 2

21 (10.9)

56 (25.5)

3.403 (1.938–5.975)

< 0.001

NLR

    

 < 6.54

76 (39.4)

42 (19.1)

Ref

 

 ≥ 6.54

117 (60.6)

178 (80.9)

2.753 (1.767–4.288)

< 0.001

CRP (mg/L)

    

 < 98

155 (80.3)

136 (61.8)

Ref

 

 ≥ 98

38 (19.7)

84 (38.2)

2.519 (1.611–3.939)

< 0.001

  1. p value of ≤ 0.05 was considered to be statistically significant and shown in bold
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