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Table 3 Odds ratio for COPD by telomere length quartiles-NHANES 1999–2002

From: The association between leukocyte telomere length and chronic obstructive pulmonary disease is partially mediated by inflammation: a meta-analysis and population-based mediation study

Telomere length

COPD

N

cOR (95% CI)

aOR (95% CI)a

Male + Femaleb

455

  

 Q4

82

1.00

1.00

 Q3

95

1.03 (0.72–1.45)

0.95 (0.66–1.36)

 Q2

116

1.55 (1.19–2.01)

1.35 (0.99–1.86)

 Q1

162

2.14 (1.67–2.74)

1.68 (1.19–2.37)

P for trend

 

 < 0.01

< 0.01

 Male

171

  

 Q4

27

1.00

1.00

 Q3

30

0.97 (0.48–1.95)

0.90 (0.45–1.81)

 Q2

45

1.37 (0.87–2.16)

1.28 (0.77–2.14)

 Q1

69

2.11 (1.41–3.15)

1.72 (0.98–3.00)

P for trend

 

< 0.01

0.04

Female

284

  

 Q4

55

1.00

1.00

 Q3

65

1.04 (0.69–1.57)

0.95 (0.62–1.45)

 Q2

71

1.69 (1.20–2.38)

1.41 (0.95–2.12)

 Q1

93

2.21 (1.55–3.14)

1.64 (1.07–2.51)

P for trend

 

 < 0.01

< 0.01

  1. cOR Crude odds ratio; aOR Adjusted odds ratio; CI confidence interval; N Number; NHANES National Health and Nutrition Examination Survey
  2. aModel was adjusted for age, age square, education, race, poverty income ratio, body mass index, smoking status, alcohol-use status, diabetes status, high blood pressure status and physical activity status
  3. bSex was further adjusted