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Table 3 Correlations between ACOX2 mRNA expression and mutation of key genes in NSCLC. Gene Expression Correlations

From: Altered expression of ACOX2 in non-small cell lung cancer

 

Mutated Gene

LUAD

LUSC

Partial cor

p-value

Partial cor

p-value

ACOX2

TP53

 − 0.272

1.8 × 10–10

 − 0.321

0.0073

KRAS

0.168

0.00035

0.929

0.0042

EGFR

0.168

0.012

0.929

0.66

ERBB2

0.022

0.93

 − 1.112

0.0091

PIK3CA

 − 0.158

0.13

 − 0.137

0.3

ALK

 − 0.126

0.068

 − 0.513

0.035

ROS1

 − 0.358

0.0014

0.165

0.067

CDKN2A

 − 0.247

0.044

 − 0.251

0.049

PTEN

 − 0.192

0.83

 − 0.014

0.61

BRAF

 − 0.07

0.37

 − 0.378

0.25

MET

 − 0.303

0.06

0.109

0.56

NF1

 − 0.017

0.49

0.094

0.5

  1. Analysis was conducted using TIMER 2.0 [44]
  2. Any correlates/analyses meeting the threshold for significance (p < 0.05) have been highlighted in bold text
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BMC Pulmonary Medicine

ISSN: 1471-2466

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