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Table 4 Correlations between ACOX2 and immune infiltrations in NSCLC

From: Altered expression of ACOX2 in non-small cell lung cancer

(a) Gene Correlations

 

Variable

LUAD

LUSC

Partial cor

p-value

Partial cor

p-value

ACOX2

Purity

0.060729633

0.17778443

 − 0.387756565

1.34 × 10–18 ***

B Cell

0.061510052

0.176694922

0.144611112

0.001632704**

CD8 + T cell

 − 0.123441444

0.006380587**

0.237579471

1.61 × 10–7***

CD4 + T cell

0.064108492

0.159075162

0.351217599

3.09E − 15***

Macrophage

0.001779846

0.968813906

0.458092406

4.03E − 26***

Neutrophil

 − 0.092574269

0.04198932*

0.361723863

3.68E − 16***

Dendritic cell

0.017626312

0.69771296

0.423935124

4.25E − 22***

(B) Survival

 

Variable

LUAD

LUSC

p-value

p-value

ACOX2

B Cell

0.000268 **

0.778204

CD8 + T Cell

0.345905

0.370702

CD4 + T Cell

0.507773

0.142871

Macrophage

0.110109

0.651048

Neutrophil

0.081069

0.126999

Dendritic Cell

0.047524 *

0.324067

USO1

0.091429

0.240999

  1. (Analysis was conducted using TIMER [47]). Results are presented as purity-corrected partial Spearman’s rho value and statistical significance
  2. Any correlates/analyses meeting the threshold for significance (p < 0.05) have been highlighted in bold text
  3. *p < 0.05; **p < 0.01; ***p < 0.001
  4. Partial Cor.—partial correlation (partial Spearman’s rho value) (Analysis was conducted using TIMER). Results are presented as purity-corrected partial Spearman’s rho value and statistical significance
  5. *p < 0.05; **p < 0.01; ***p < 0.001. Partial Cor. partial correlation (partial Spearman’s rho value)
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BMC Pulmonary Medicine

ISSN: 1471-2466

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