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Table 4 The cell cycle of different generations in 16HBE-B control group and CSE-exposed group

From: Strategies for understanding the role of cellular heterogeneity in the pathogenesis of lung cancer: a cell model for chronic exposure to cigarette smoke extract

16HBE-B passage

Control group

CSE group

Chi-square

P

G1 (%)

S (%)

G2 (%)

G1 (%)

S (%)

G2 (%)

1

74.99

17.7

7.31

75.59

18.13

6.28

0.058

0.809

5

78.94

16.42

4.64

80.87

12.32

6.80

0

0.999

10

71.07

21.79

7.14

75.45

19.14

5.41

0.657

0.417

20

70.22

24.68

5.10

63.80

28.20

8.00

1.098

0.293

30

64.16

24.69

11.15

56.67**

32.33**

11.00**

0.521

0.470

40

61.87

28.46

9.67

43.28**ΔΔ

41.61**ΔΔ

15.11**ΔΔ

5.878

0.015

  1. *P ≤ 0.05, n = 3; **P ≤ 0.01, n = 3 versus P1 CES Group; P: CSE Group versus Control Group
  2. ΔP ≤  0.05, n = 3, ΔΔP ≤ 0.01, n = 3 versus CSE Group versus Control Group