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Table 5 The cell cycle of different generations in 16HBE-S control group and CSE-exposed group

From: Strategies for understanding the role of cellular heterogeneity in the pathogenesis of lung cancer: a cell model for chronic exposure to cigarette smoke extract

16HBE-S passage

Control group

CES group

Chi-square

P

G1 (%)

S (%)

G2 (%)

G1 (%)

S (%)

G2 (%)

1

77.34

17.66

5.00

77.85

14.15

8.00

0.0595

0.807

5

81.37

15.92

2.70

84.21

11.36

4.42

0.167

0.682

10

80.64

13.98

5.37

82.18

14.93

2.89

0.177

0.674

20

78.81

15.26

5.94

64.92

27.08

8.00

3.483

0.062

30

69.33

22.67

8.00

56.39**Δ

29.07**Δ

14.54**Δ

4.168

0.041

40

66.32

22.68

11.00

43.17**Δ

35.38**Δ

21.45**Δ

9.565

0.002

  1. *P ≤ 0.05, n = 3; **P ≤ 0.01, n = 3 versus P1 CES Group; P: CSE Group versus Control Group
  2. ΔP ≤ 0.05, n = 3; ΔΔP ≤ 0.01, n = 3 versus CSE Group versus Control Group