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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: METTL3 promotes non-small cell lung cancer (NSCLC) cell proliferation and colony formation in a m6A-YTHDF1 dependent way

Fig. 3

FRAS1 protein not mRNA level was decreased in METTL3-silenced cells. A The protein levels of METTL3 and FRAS1 were measured in METTL3-knockdown HCC827 and NCI-H1975 cells. B The mRNA level of METTL3 was determined in shMETTL3 HCC827 and NCI-H1975 cells by qPCR. C The protein level of FRAS1 was detected in METTL3-knockdown HCC827 and NCI-H1975 cells treated with ActD at 0, 30, 60, 120 min. D CCK-8 assay was performed in shMETTL3 HCC827 and NCI-H1975 cells. (E) Colony formation was performed in shMETTL3 HCC827 and NCI-H1975 cells for 4 days culture. *P < 0.05 or **P < 0.01 or ***P < 0.001 indicates a significant difference between the indicated groups. ns, not significant

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BMC Pulmonary Medicine

ISSN: 1471-2466

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