Table 3 Variables and diagnostic accuracy for HFNC outcomes (n = 111)
No. of patients who remain on HFNC | HFNC success | No. of patients who remain on HFNC | HFNC failure | P value | AUROC | ||
|---|---|---|---|---|---|---|---|
ROX | Before Initiation of HFNC | 72 | 8.83 (6.19–11.81) | 39 | 6.81 (5.65–9.72) | 0.075 | 0.604 (0.494–0.713) |
2 h | 72 | 9.54 (7.77–12.97) | 39 | 7.83 (6.33–10.43) | 0.006** | 0.659 (0.553–0.765) | |
6 h | 70 | 11.28 (9.58–14.86) | 27 | 7.33 (6.11–9.80) | < 0.001** | 0.759 (0.645–0.873) | |
12 h | 62 | 11.57 (9.36–13.61) | 15 | 8.17 (6.53–10.56) | < 0.001** | 0.767 (0.617–0.916) | |
18 h | 50 | 11.42 (9.67–13.89) | 11 | 7.22 (5.39–10.33) | 0.001** | 0.815 (0.682–0.947) | |
24 h | 38 | 11.83 (8.65–15.61) | 7 | 7.70 (5.54–12.93) | 0.052 | 0.733 (0.525–0.941) | |
Post-HFNC initiation ROX## | 72 | 10.16 (8.02–12.50) | 39 | 8.04 (6.39–10.86) | 0.036* | 0.621 (0.505–0.737) | |
Delta ROX## | 72 | 1.78 (-0.61–5.03) | 39 | 0.32 (-3.65–1.85) | 0.001** | 0.690 (0.590–0.790) | |
POX | Pre-HFNC POX# | 72 | 7.39 (5.04–11.33) | 39 | 5.38 (3.60–7.00) | < 0.001** | 0.705 (0.608–0.803) |
Post-HFNC POX## | 72 | 8.47 (6.32–10.95) | 39 | 5.96 (4.16–8.57) | < 0.001** | 0.702 (0.594–0.811) | |
POX-HR | Pre-HFNC POX-HR# | 72 | 8.87 (5.05–12.58) | 39 | 5.28 (3.64–6.85) | < 0.001** | 0.714 (0.619–0.810) |
Post-HFNC POX-HR## | 72 | 9.35 (6.85–12.22) | 39 | 5.98 (4.26–7.97) | < 0.001** | 0.726 (0.622–0.829) | |
Delta POX-HR## | 72 | 3.29 (0.61–5.34) | 39 | − 1.12 (− 3.99–1.63) | < 0.001** | 0.813 (0.726–0.900) | |