Comparison of ROX index (SpO2/FIO2 ratio/respiratory rate) with a modified dynamic index incorporating PaO2/FIO2 ratio and heart rate to predict high flow nasal cannula outcomes among patients with acute respiratory failure: a single centre retrospective study

Table 5 Cox regression analysis evaluating Delta POX-HR > 0.10 and post-HFNC POX-HR > 6.80 for the prediction of HFNC failure in patients with ARF

	Univariate Analysis	P value	Multivariate Analysis	P value
Delta POX-HR > 0.1	0.178 (0.088–0.360)	< 0.001**	0.236 (0.113–0.492)	< 0.001**
Post-HFNC POX-HR > 6.80	0.281 (0.084–0.748)	0.018*	0.363 (0.159–0.964)	0.042*

^*P value < 0.05; **P value < 0.01
Other variables included in the multivariate analysis: age, gender, pre-HFNC POX-HR index, and APACHE II score

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