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Table 6 Cut-off for high risk of HFNC failure for change in POX-HR and post-HFNC POX-HR with > 90% specificity

From: Comparison of ROX index (SpO2/FIO2 ratio/respiratory rate) with a modified dynamic index incorporating PaO2/FIO2 ratio and heart rate to predict high flow nasal cannula outcomes among patients with acute respiratory failure: a single centre retrospective study

 

Cut-off

Sensitivity (%)

Specificity (%)

NPV (%)

PPV (%)

Youden Index

Delta POX-HR

− 1.20

46.2%

90.3%

75.6%

72.0%

0.365

Post-HFNC POX-HR

5.00

38.5%

91.7.0%

73.3%

71.4.0%

0.302

  1. NPV Negative predictive value, PPV Positive predictive value