Table 3 Factors associated with survival
Hazard ratio (95% confidence interval) | p-value | |
|---|---|---|
First-degree family member with pulmonary fibrosis (n = 116) | 1.18 (0.86–1.63) | 0.30 |
Other family member with pulmonary fibrosis (n = 24) | 1.35 (0.69–2.63) | 0.38 |
Any family member with pulmonary fibrosis (n = 125) | 1.18 (0.86–1.62) | 0.29 |
Current smoker (n = 33) * | 0.46 (0.21–0.97) | 0.04 |
Former smoker (n = 298) * | 1.01 (0.68–1.50) | 0.97 |
Significant exposure to asbestos, dusts, fumes, or radiation (n = 79) | 1.12 (0.85–1.47) | 0.44 |
Gastro-oesophageal reflux (n = 149) | 0.98 (0.75–1.30) | 0.91 |
Cardiovascular disease (n = 188) | 1.41 (1.07–1.86) | 0.01 |
Chest X-ray prior to start of symptoms showing potential interstitial lung abnormalities (n = 56) # | 1.65 (0.88–3.08) | 0.56 |
CT-scan prior to start of symptoms showing potential interstitial lung abnormalities (N = 34) $ | 0.98 (0.37–2.58) | 0.97 |
Symptoms started directly after infectious episode (n = 40) | 0.82 (0.51–1.34) | 0.43 |
Symptoms started directly after surgery (n = 5) | 0.65 (0.16–2.64) | 0.55 |
Treatment with steroids prior to diagnosis (n = 103) ^ | 1.10 (0.81–1.49) | 0.55 |
Treatment with other immunosuppressant prior to diagnosis (n = 23) | 0.94 (0.53–1.65) | 0.82 |
Other ILD diagnosis prior to diagnosis of IPF (n = 67) | 1.01 (0.71–1.44) | 0.96 |
Cardiology workup for symptoms prior to pulmonology visit (n = 45) | 0.96 (0.64–1.44) | 0.83 |
Time from start of symptoms to first visit with pulmonologist (n = 409) | 1.00 (0.99–1.01) | 0.81 |
Time from start of symptoms to diagnosis (n = 409) | 1.00 (1.00–1.00) | 0.97 |
Consensus diagnosis of IPF (n = 190) | 0.89 (0.68–1.17) | 0.40 |
Received treatment with antifibrotic therapy after diagnosis | 0.52 (0.37–0.75) | < 0.001 |