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Table 3 The characteristics of biopsied benign and malignant nodules

From: Prevalence and clinical characteristics of malignant lung nodules in tuberculosis endemic area in a single tertiary centre

Characteristics

Benign, n (%) n = 22 (45%)

Malignant, n (%) n = 27 (55%)

p-value

Age, median (IQR)

68.5 (17.5)

72 (11)

0.144b

Sex, n (%)

Male

15 (53.6)

13 (46.4)

0.159

Female

7 (33.3)

14 (66.7)

 

Family history of Lung cancer, n (%)

Yes

1 (100.0)

0

0.449a

No

21 (43.8)

27 (56.3)

 

Smoking, n (%)

Active smoker

6 (85.7)

1 (14.3)

0.087

Non-smoker

11 (35.5)

20 (64.5)

 

Ex-smoker

 Stop < 15 years

2 (66.7)

1 (33.3)

 

 Stop > 15 years

3 (37.5)

5 (62.5)

 

Nodule size (cm), median (IQR)

1.7 (1.02)

2.0 (1.4)

0.146b

Location, n (%)

Upper lobe

15 (57.7)

11 (42.3)

0.155

Middle lobe

1 (25.0)

3 (75.0)

 

Lower lobe

6 (31.6)

13 (68.4)

 

Multiplicity, n (%)

Single nodule

6 (54.5)

5 (45.5)

0.348a

Multiple nodules

16 (42.1)

22 (57.9)

 

Density, n (%)

Solid

22 (44.9)

27 (55.1)

Subsolid

0

0

 

Presence of spiculation, n (%)

Yes

10 (43.5)

13 (56.5)

0.851

No

12 (46.2)

14 (53.8)

 

Emphysema, n (%)

Yes

1 (33.3)

2 (66.7)

0.678a

No

21 (45.7)

25 (54.3)

 

Biopsy method, n (%)

CT Guided biopsy

22 (47.8)

24 (52.2)

0.242a

Others*

0

3 (100.0)

 

Complications, n (%)

Yes

 Pneumothorax

1 (14.3)

6 (85.7)

0.127

 Subcutaneous emphysema

1 (100.0)

0

 

No

20 (48.8)

21 (51.2)

 
  1. aFishers exact test bMann-Whitney test. Other analyses using Pearson chi-square test
  2. *Others, i.e., Transbronchial needle biopsy