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Table 3 Optional cut-off values of the variables

From: Establishment and validation of nomogram for predicting immuno checkpoint inhibitor related pneumonia

 

Cut-off value

Sensitivity (%)

Specificity (%)

Youden index

AUC (95%CI)

P

IL-6

> 64.85 (pg/ml)

50.00

88.00

0.38

0.69 (0.63–0.75)

< 0.01

CRP

> 107.24 (mg/L)

45.00

77.33

0.22

0.59 (0.53–0.65)

0.14

CD8 + T

> 1106 (/ul)

40.00

86.67

0.27

0.62 (0.56–0.68)

0.09

SP-A

> 72.24 (ng/ml)

55.00

81.33

0.36

0.64 (0.58–0.70)

0.09

SP-D

> 267.79 (ng/ml)

80.00

59.11

0.39

0.68 (0.61–0.71)

< 0.01

KL-6

> 508 (U/ml)

75.00

87.56

0.63

0.81 (0.76–0.86)

< 0.01

  1. IL-6 interleukin-6, CRP C-reaction protein, SP-A sufactant protein A, KL-6 Krebs Von den Lungen-6, AUC area under curve