Identification of early biomarkers of transcriptomics in alveolar macrophage for the prognosis of intubated ARDS patients

Table 1 Survival analysis of the top 10 up-regulated and down-regulated genes

	Genes	OR	Lower 95%	Upper 95%	p value
Top 10 of the up-regulated DEGs	SSH2	0.516	0.166	1.603	0.252
	FKBP5	1.102	0.313	3.882	0.879
	TSC22D3	0.368	0.048	2.827	0.337
	DDIT4L (cut-off = 9.305)	1.862	0.487	7.116	0.363
	DDIT4L (cut-off = 8.951)	0.692	0.269	1.780	0.445
	ICA1	0.757	0.217	2.636	0.662
	FRAT1	0.512	0.194	1.347	0.175
	ADORA3	2.285	0.926	8.614	0.068*
	TFCP2L1	0.918	0.302	2.794	0.881
	FARP1	0.607	0.235	1.566	0.301
	PP2447	0.757	0.268	2.141	0.600
Top 10 of the down-regulated DEGs	KIAA0256	0.614	0.240	1.571	0.309
	AMFR (cut-off = 10.391)	1.120	0.440	2.851	0.812
	AMFR (cut-off = 10.614)	0.760	0.293	1.968	0.571
	CTSZ	0.907	0.258	3.195	0.879
	PPP3R1	0.564	0.217	1.465	0.239
	MYOM2 (cut-off = 9.843)	2.715	0.354	20.840	0.337
	MYOM2 (cut-off = 10.211)	0.877	0.287	2.678	0.818
	MYOM2 (cut-off = 10.348)	0.883	0.337	2.314	0.800
	MYOM2 (cut-off = 10.751)	0.728	0.286	1.852	0.505
	UNC45A	1.152	0.332	4.004	0.824
	CD86	0.414	0.119	1.444	0.166
	C21orf57	0.719	0.253	2.044	0.535
	IL18BP	0.786	0.302	2.047	0.622
	DCAL1	0.632	0.141	2.842	0.550

ISSN: 1471-2466