From: Prognostic value of lymphocyte count for in-hospital mortality in patients with severe AECOPD
Variables | Total (N = 458) | Lymphocyte count < 0.8 × 109/L (N = 175) | Lymphocyte count > 0.8 × 109/L (N = 283) | p value |
---|---|---|---|---|
Age, years | 78.2 (8.2) | 79.2 (7.4) | 77.5 (8.6) | 0.036 |
Male | 334 (72.9%) | 131 (74.9%) | 203 (71.7%) | 0.464 |
Smoking status | 0.115 | |||
Never smoker | 110 (20.0%) | 38 (21.7%) | 72 (25.4%) | |
Former smoker | 292 (63.8%) | 131 (74.9%) | 161 (56.9%) | |
Current smoker | 56 (12.2%) | 20 (11.4%) | 36 (12.7%) | |
BMI, kg/m2 | 23.2 (4.7) | 22.7 (4.7) | 23.5 (4.7) | 0.060 |
Long-term home oxygen therapy | 103 (22.5%) | 49 (28.0%) | 54 (19.1%) | 0.026 |
ADL index at admission | 43 (29.7) | 35.9 (27.6) | 47.5 (30.1) | < 0.001 |
Exacerbation history in the past year | 197 (43.0%) | 76 (43.4%) | 121 (42.8%) | 0.888 |
Regular use of long-acting bronchodilators | 105 (22.9%) | 47 (26.8%) | 58 (20.5%) | 0.116 |
Oral steroid before admission | 45 (9.8%) | 19 (10.9%) | 26 (9.2%) | 0.560 |
Oral antibiotics before admission | 99 (21.6%) | 44 (25.1%) | 55 (19.4%) | 0.149 |
Requirement for IMV | 64 (14.0%) | 31 (17.7%) | 33 (11.7%) | 0.069 |
Body temperature, °C | 36.5 (0.5) | 36.6 (0.6) | 36.5 (0.5) | 0.239 |
Pulse, bpm | 89.4 (15.8) | 91.7 (16.4) | 87.9 (15.2) | 0.012 |
Respiratory rate, bpm | 21.4 (5.4) | 22.0 (5.0) | 21.0 (5.6) | 0.056 |
Systolic pressure, mmHg | 134.1 (20.2) | 134.8 (21.7) | 133.7 (19.3) | 0.555 |
Diastolic pressure, mmHg | 72.9 (11.5) | 72.6 (11.7) | 73.0 (11.4) | 0.750 |
Comorbidities | ||||
Respiratory failure | 352 (76.9%) | 148 (84.6%) | 204 (72.1%) | 0.002 |
Hypertension | 265 (57.9%) | 96 (54.z9%) | 169 (59.7%) | 0.306 |
CHD | 141 (30.8%) | 49 (28.0%) | 92 (32.5%) | 0.310 |
CHF | 119 (26.0%) | 54 (30.9%) | 65 (23.0%) | 0.061 |
Atrial fibrillation | 86 (18.8%) | 38 (21.7%) | 48 (17.0%) | 0.206 |
Diabetes | 115 (25.1%) | 53 (30.8%) | 62 (21.9%) | 0.045 |
CKD | 71 (15.5%) | 36 (20.6%) | 35 (12.4%) | 0.018 |
GER | 82 (17.9%) | 36 (20.6%) | 46 (16.3%) | 0.242 |
Anemia | 55 (12.0%) | 30 (17.1%) | 25 (8.8%) | 0.008 |
SAHS | 30 (6.6%) | 8 (4.6%) | 22 (7.8%) | 0.178 |