Hyoid bone position as an indicator of severe obstructive sleep apnea

BMC Pulmonary Medicine

Table 3 Sensitivity, specificity, PPV, NPV, and error rate of clinical and hyoid bone position indices in evaluating severe obstructive sleep apnea

Cut-off value		OSA group		AUC	Sensitivity (%) [95% CI]	Specificity (%) [95% CI]	PPV (%) [95% CI]	NPV (%) [95% CI]	Error rate (%)	p-value
Cut-off value		Severe	Mild to moderate	AUC	Sensitivity (%) [95% CI]	Specificity (%) [95% CI]	PPV (%) [95% CI]	NPV (%) [95% CI]	Error rate (%)	p-value
Distance from hyoid bone to mandibular plane	≥ 19.45 mm	29	38	0.632	61.7 [46.4, 75.5]	55.8 [44.7, 66.5]	43.3 [35.5, 51.4]	72.7 [63.9, 80.1]	42.1	0.040*
Distance from hyoid bone to mandibular plane	< 19.45 mm	18	48	0.632	61.7 [46.4, 75.5]	55.8 [44.7, 66.5]	43.3 [35.5, 51.4]	72.7 [63.9, 80.1]	42.1	0.040*
Age	≥ 45 years	29	32	0.663	61.7 [46.4, 75.5]	62.8 [51.7, 73.0]	47.5 [38.9, 56.4]	75.0 [66.8, 81.7]	37.6	0.007**
Age	< 45 years	18	54	0.663	61.7 [46.4, 75.5]	62.8 [51.7, 73.0]	47.5 [38.9, 56.4]	75.0 [66.8, 81.7]	37.6	0.007**
BMI	≥ 25 kg/m²	32	39	0.688	69.6 [54.3, 82.3]	54.1 [43.0, 65.0]	45.1 [37.8, 52.6]	76.7 [67.1, 84.1]	40.5	0.009**
BMI	< 25 kg/m²	14	46	0.688	69.6 [54.3, 82.3]	54.1 [43.0, 65.0]	45.1 [37.8, 52.6]	76.7 [67.1, 84.1]	40.5	0.009**
ESS	≥ 9	23	31	0.547	50.0 [34.9, 65.1]	61.7 [50.3, 72.3]	42.6 [33.2, 52.5]	68.5 [60.8, 75.3]	42.5	0.199
ESS	< 9	23	50	0.547	50.0 [34.9, 65.1]	61.7 [50.3, 72.3]	42.6 [33.2, 52.5]	68.5 [60.8, 75.3]	42.5	0.199

Sensitivity was obtained from TP/(TP + FN) × 100, Specificity was obtained from TN/(TN + FP) × 100, PPV was obtained from TP/(TP + FP) × 100, NPV was obtained from TN/(TN + FN) × 100, Error rate was obtained from (FN + FP)/(TN + TP + FN + FP)
OSA Obstructive sleep apnea; AUC Area under the curve; CI Confidence internal; BMI Body mass index; ESS Epworth sleepiness scale
*Significant difference: p < 0.05
**Significant difference: p < 0.01

ISSN: 1471-2466