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Table 3 Incidence rates, hazard ratio and confidence intervals of diaphragmatic hernia in different stratification

From: Risk of diaphragmatic hernia in patients with spontaneous pneumothorax

Variables

Matched cohort

Pneumothorax

HR

n = 46,897

n = 46,897

Crude

p value

Adjusted

p value

Event

Person years

IR

Event

Person years

IR

(95% CI)

 

(95% CI)

 

Age at baseline

 < 40

10

110,528

0.90

14

106,107

1.32

1.46 (0.65–3.29)

0.360

1.51 (0.67–3.41)

0.318

40–64

13

69,029

1.88

18

39,739

4.53

2.39 (1.17–4.89)

0.017

2.61 (1.27–5.36)

0.009

 ≥ 65

97

104,241

9.31

66

36,345

18.16

1.85 (1.34–2.53)

 < 0.001

1.97 (1.43–2.71)

 < 0.001

Gender

Female

24

58,723

4.09

14

33,679

4.16

1.00 (0.52–1.93)

0.997

1.75 (0.89–3.46)

0.105

Male

96

225,076

4.27

84

148,512

5.66

1.30 (0.97–1.74)

0.081

2.11 (1.56–2.85)

 < 0.001

Comorbidity

Hypertension

51

50,045

10.19

32

15,815

20.23

1.89 (1.20–2.97)

0.006

2.05 (1.30–3.23)

0.002

Diabetes mellitus

22

26,633

8.26

18

8852

20.33

2.43 (1.29–4.56)

0.006

2.58 (1.37–4.86)

0.004

Hyperlipidemia

4

9431

4.24

4

3614

11.07

2.78 (0.69–11.26)

0.151

3.21 (0.78–13.24)

0.107

Smoking related diseases

76

66,553

11.42

46

22,646

20.31

1.71 (1.18–2.48)

0.005

1.86 (1.28–2.71)

0.001

  1. Adjusted HR: adjusted for gender, age, and comorbidities in Cox proportional hazards regression
  2. IR Incidence rates, per 10,000 person-years, HR Hazard ratio, CI Confidence interval