Table 2 Predictive factors for the diagnosis of a target disease compared to all other diseases
From: Characteristics of pleural effusion with a high adenosine deaminase level: a case–control study
Factor | Odds ratio | 95% Cl | Sensitivity | Specificity | p-value | |
|---|---|---|---|---|---|---|
Upper limit | Lower limit | |||||
TB | ||||||
Pleural fluid LDH < 825 IU/L | 12.90 | 6.47 | 25.50 | 79.3 | 79.4 | < 0.001 |
Pleural fluid LDH/ADA < 26 | 4.44 | 2.12 | 9.31 | 93.1 | 56.1 | < 0.001 |
Pleural infection | ||||||
Neutrophil predominance or cell degeneration | 44.60 | 19.50 | 102.00 | 92.9 | 81.7 | < 0.001 |
WBC ≥ 9,200/µL or CRP ≥ 12 mg/dL | 18.60 | 8.37 | 41.10 | 91.1 | 72.6 | < 0.001 |
Malignant pleural effusion | ||||||
Pleural fluid amylase ≥ 75 U/L | 13.30 | 5.81 | 30.40 | 49.0 | 92.2 | < 0.001 |
Pleural fluid ADA/TP < 14 | 17.90 | 6.90 | 46.60 | 88.9 | 67.9 | < 0.001 |
NTM | ||||||
Pneumothorax | 17.60 | 6.99 | 44.10 | 59.1 | 92.4 | < 0.001 |
ML | ||||||
Serum LDH ≥ 315 IU/L | 31.70 | 10.00 | 101.00 | 77.8 | 90.1 | < 0.001 |
Autoimmune diseases | ||||||
Serum Eo ≥ 4.4% and Pleural fluid Eo ≥ 2.0% | 58.30 | 14.10 | 241.00 | 72.7 | 95.6 | < 0.001 |
Other diseases | ||||||
Pleural calcification | 16.70 | 5.01 | 56.00 | 22.2 | 98.1 | < 0.001 |
Pneumothorax | 5.79 | 2.30 | 14.60 | 33.3 | 91.4 | < 0.001 |