Fig. 2

Alterations of mean arterial blood pressure (MBP, A) and heart rate (HR, C) during 60 min’ induction of lung injury in all lavage groups, and with equal duration in the Sham and SPX groups. The mean values of MBP (B) and HR (D) were compared 5 min before the starting point (pre) and 5 min after the 10th lavage (post), and with the same duration in the Sham and SPX groups without lavage. n = 10 in each group. Data are mean ± SD. *: P < 0.05, each group versus the Sham group; ×: P < 0.05, each group versus the SPX group; †: P < 0.05, the post values versus the pre values. LAV Lavage; NIC Nicotine; SPX Splenectomy; MLA Methyllycaconitine