Table 1 Demographics and clinical features of the enrolled LAM patients
From: Gene mutations in sporadic lymphangioleiomyomatosis and genotype–phenotype correlation analysis
Characteristics | Ratio (%) or median (range) or mean ± SD |
|---|---|
Sex | |
Female, n (%) | 22 (100.0%) |
Ethnic | |
Asian, n (%) | 22 (100.0%) |
aAge, median (range) (year) | 38.5 (25–57) |
Postmenopause, n (%) | 2 (9.1%) |
Smoking history, n (%) | 0 (0.0%) |
Pneumothorax, n (%) | 11(50.0%) |
Chylous effusions, n (%) | 3 (13.6%) |
Renal angiomyolipoma, n (%) | 4 (18.2%) |
bLymphangioleiomyomas, n (%) | 16 (72.7%) |
cRapamycin therapy, n (%) | 0 (0.0%) |
Serum VEGF-D, mean ± SD (pg/ml) | 1719.0 ± 1311.4 |
FEV1% pred, mean ± SD (%) | 76.3 ± 19.0 |
DLCO % pred, mean ± SD (%) | 59.8 ± 22.9 |
6MWD (meters) | 493.1 ± 86.1 |
CT grading | |
Grade I, n (%) | 5 (22.7%) |
Grade II, n (%) | 7 (31.8%) |
Grade III, n (%) | 10 (45.5%) |