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Table 2 Independent predictors of in-hospital mortality by univariate and multivariate Cox regression analysis

From: Mean platelet volume as a predictive biomarker for in-hospital mortality in patients receiving invasive mechanical ventilation

Variables

HR (95%CI)

P

Univariate Cox analysis

APACHE II score

1.046 (1.001–1.092)

0.043

Albumin

1.016 (0.963–1.072)

0.561

Creatinine

1.001 (1.000–1.002)

0.214

MPV

1.712 (1.358–2.159)

0.000

Leukocyte

0.982 (0.908–0.993)

0.657

CRP

1.011 (1.003–1.020)

0.011

Vasopressor use

2.087 (1.115–3.908)

0.021

CRRT

3.134 (1.193–8.232)

0.003

CKD

2.052 (1.017–4.140)

0.045

Septic shock

2.538 (1.371–4.697)

0.003

AKI

1.949 (1.051–3.612)

0.034

PaO2/FIO2

0.982 (0.971–0.993)

0.002

Age

1.028 (1.000–1.057)

0.052

Lactate

1.080 (0.953–1.223)

0.228

sex

0.849 (0.447–1.613)

0.849

Multivariate Cox* analysis

MPV

1.741 (1.267–2.393)

0.001

PaO2/FIO2

0.984 (0.972–0.997)

0.015

CRP

1.013 (1.003–1.022)

0.008

CRRT

5.455 (1.676–17.759)

0.005

  1. *Covariates included in multivariate analysis: APACHE II score, MPV, CRP, PaO2/FIO2, vasopressor use, CRRT, CKD, AKI, septic shock
  2. APACHE II acute physiology and chronic health evaluation II; MPV mean platelet volume; CRP C-reactive protein; CRRT continuous renal replacement therapy; CKD chronic kidney disease; AKI acute kidney injury; PaO2 arterial oxygen tension; FiO2 fraction of inspired oxygen;
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BMC Pulmonary Medicine

ISSN: 1471-2466

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