Fig. 1

cBioPortal database was used for analyzing EPHA5 mutation type. Mutation diagram circles are colored with respect to the corresponding mutation types. In case of different mutation types at a single position, color of the circle is determined with respect to the most frequent mutation type (A). Mutual exclusivity and co-occurrence analysis. X-axis indicated that the altered frequency of genes in EPHA5 mutation patients and Y-axis revealed that in wild-type EPHA5 ones (the blue dot represents the specific gene mutation with significant P value) (B). The mutation frequency of related genes in the EPHA5 mutant and wild-type groups (* represents the difference meaningful) (C)