Prediction of exercise-induced desaturation in COPD patients without resting hypoxemia: a retrospective study

BMC Pulmonary Medicine

Table 3 Univariate and multiple logistic regression analysis of EID

Variables	EXP(B)	95%C.I	P	EXP(B)	95%C.I	P
gender	0.752	0.300–1.883	0.542
Age (y)	1.011	0.976–1.047	0.559
BMI (kg/m²)	0.951	0.862–1.100	0.282
SpO_2rest (%)	1.069	0.907–1.260	0.428
6MWD (m)	0.994	0.990–0.998	0.005	0.996	0.992–1.000	0.071
FVC% pred	0.999	0.983–1.016	0.914
FEV1% pred	0.993	0.979–1.008	0.356
D_LCO SB% pred (%)	0.973	0.956 ~ 0.990	0.002	0.970	0.952–0.988	0.001
D_LCO/VA% pred (%)	0.967	0.950–0.985	< 0.001	0.962	0.940–0.985	0.002
mMRC dyspnea scale	1.453	1.007–2.097	0.046	1.195	0.693–2.061	0.522
CAT score	1.121	1.055–1.3192	< 0.001	1.142	1.052–1.241	0.002
BODE index	1.193	0.999–1.424	0.051
mean density (HU)	0.983	0.968–0.999	0.036	0.985	0.969–1.000	0.048
PD15 (HU)	0.982	0.967–0.997	0.016	0.983	0.968–0.999	0.033
emphysema volume (ml)	1.001	1.000–1.001	0.019	1.001	1.000–1.001	0.049
%LAA (%)	1.052	1.011–1.093	0.012	1.045	1.004–1.089	0.033

EID Exercise-induced desatuation; BMI Body mass index; 6MWD 6 min-walk distance; SpO_2rest Resting blood oxygen saturation at the beginning of the test; FVC% pred Forced vital capacity as a percentage of predicted value; FEV1% pred Forced expiratory volume in the first second as a percentage of predicted value; D_LCO SB% pred Lung carbon monoxide diffusion as a percentage of predicted value; D_LCO/VA% pred Lung carbon monoxide diffusion per liter of alveolar air volume as a percentage of predicted value; mMRC Modified Medical Research Council; CAT COPD Assessment Test; PD15 15th percentile point; %LAA % low attenuation areas

ISSN: 1471-2466