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Table 5 Cough-related diseases in the preindex period and in Months 10 to 12 of the post-index period

From: Clinical characteristics and drug utilisation patterns in patients with chronic cough: a retrospective cohort study using a Japanese claims database

Population/ subgroup

Population ‘All’

Population 1

Population 2

Other coughs

Cough-variant asthma

Atopic/allergic cough

Period

Pre-index

M10-12

Pre-index

M10-12

Pre-index

M10-12

Pre-index

M10-12

Pre-index

M10-12

Pre-index

M10-12

Number of participants1

N = 6,038

N = 2,804

N = 3,500

N = 1,284

N = 2,538

N = 1,520

N = 1,444

N = 856

N = 1,026

N = 615

N = 105

N = 63

ARNI

3,826 (63.4%)

1,975 (70.4%)

2,093 (59.8%)

899 (70.0%)

1,733 (68.3%)

1,076 (70.8%)

950 (65.8%)

600 (70.1%)

737 (71.8%)

448 (72.8%)

77 (73.3%)

44 (69.8%)

Asthma

2,920 (48.4%)

1,179 (42.0%)

1,778 (50.8%)

533 (41.5%)

1,142 (45.0%)

646 (42.5%)

640 (44.3%)

358 (41.8%)

453 (44.2%)

259 (42.1%)

64 (61.0%)

31 (49.2%)

GERD

1,029 (17.0%)

574 (20.5%)

552 (15.8%)

256 (19.9%)

477 (18.8%)

318 (20.9%)

246 (17.0%)

153 (17.9%)

211 (20.6%)

149 (24.2%)

27 (25.7%)

20 (31.7%)

Paranasal sinusitis

1,037 (17.2%)

439 (15.7%)

621 (17.7%)

210 (16.4%)

416 (16.4%)

229 (15.1%)

260 (18.0%)

147 (17.2%)

149 (14.5%)

75 (12.2%)

18 (17.1%)

8 (12.7%)

CAID

586 (9.7%)

217 (7.7%)

366 (10.5%)

101 (7.9%)

220 (8.7%)

116 (7.6%)

123 (8.5%)

66 (7.7%)

88 (8.6%)

39 (6.3%)

14 (13.3%)

6 (9.5%)

Chronic rhinitis

206 (3.4%)

106 (3.8%)

106 (3.0%)

46 (3.6%)

100 (3.9%)

60 (3.9%)

72 (5.0%)

43 (5.0%)

31 (3.0%)

18 (2.9%)

0

0

Postnasal drip

127 (2.1%)

42 (1.5%)

78 (2.2%)

26 (2.0%)

49 (1.9%)

16 (1.1%)

27 (1.9%)

9 (1.1%)

21 (2.0%)

8 (1.3%)

1 (1.0%)

0

Vocal cord dysfunction

71 (1.2%)

21 (0.7%)

33 (0.9%)

8 (0.6%)

38 (1.5%)

13 (0.9%)

8 (0.6%)

1 (0.1%)

30 (2.9%)

12 (2.0%)

1 (1.0%)

0

Emphysema

62 (1.0%)

13 (0.5%)

43 (1.2%)

8 (0.6%)

19 (0.7%)

5 (0.3%)

12 (0.8%)

2 (0.2%)

5 (0.5%)

2 (0.3%)

2 (1.9%)

1 (1.6%)

Nasal polyps

10 (0.2%)

5 (0.2%)

6 (0.2%)

3 (0.2%)

4 (0.2%)

2 (0.1%)

2 (0.1%)

1 (0.1%)

2 (0.2%)

1 (0.2%)

0

0

  1. 1Defined as those participants with a cough diagnosis code or a diagnostic code for a cough-related disease during the 6-month pre-index period including the index month (pre-index period), or during the 3-month period from Month 10 to Month 12 inclusive following the index month (M10-12)
  2. Percentages are calculated with respect to the number of participants indicated at the top of the column
  3. Data in bold indicate a difference of > 5% in the proportion of participants with the cough-related disease between the pre-index period and M10-12
  4. ARNI Allergic rhinitis/nasal inflammation, CAID Chronic airway inflammatory disease, GERD Gastro-esophageal reflux disease
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