Table 2 Intraoperative and postoperative management
Characteristics | All (n = 117) | Study group | P value | |
|---|---|---|---|---|
PPCs (n = 56) | Non-PPCs (n = 61) | |||
Intraoperative management | ||||
Type of intraoperative fluid, mean (SD), ml | ||||
Crystalloid | 1905.25 (1314.06) | 1824.11 (1272.29) | 1970.00 (1376.88) | 0.554 |
Colloid* | 945.14 (607.14) | 869.70 (482.01) | 1008.97 (702.61) | 0.339 |
Blood transfusion | ||||
CRCs, mean (SD), u | 6.00 (4.15) | 4.87 (3.23) | 7.44 (4.90) | 0.064 |
Plasma, mean (SD), ml | 823.44 (806.03) | 563.89 (308.6) | 1157.14 (1123.16) | 0.040 |
Intraoperative blood loss, mean (SD), ml | 414.15 (815.46) | 348.57 (534.5) | 479.51 (1017.79) | 0.392 |
Use of vasoactive drugs** | ||||
Metaraminol, n (%) | 64.00 (54.7) | 32.00 (57.14) | 32.00 (52.46) | 0.374 |
Total Dose, mg | 0.63 (0.63) | 0.71 (0.65) | 0.55 (0.63) | 0.323 |
Ephedrine, n (%) | 39.00 (33.33) | 16.00 (28.57) | 23.00 (37.70) | 0.198 |
Total Dose, mg | 8.06 (6.68) | 8.31 (8.46) | 7.89 (5.51) | 0.851 |
Norepinephrine, n (%) | 36.00 (30.77) | 22.00 (39.29) | 14.00 (22.95) | 0.043 |
Total Dose, mg | 1.76 (2.11) | 1.73 (1.88) | 1.80 (2.56) | 0.927 |
Epinephrine, n (%) | 4.00 (3.42) | 1.00 (1.79) | 3.00 (4.92) | 0.342 |
Total Dose, mg | 101.05 (95.36) | 3.00 (0.00) | 133.73 (108.53) | 0.406 |
Use of opioids, mean (SD), µg** | ||||
Remifentanil | 1463.84 (809.02) | 1534.51 (846.83) | 1400.01 (781.54) | 0.651 |
Sufentanil | 43.91 (22.76) | 44.85 (21.93) | 43.60 (24.48) | 0.149 |
Use of muscle relaxant, mean (SD), mg** | ||||
Vecuronium bromide | 6.06 (4.95) | 3.65 (4.74) | 7.67 (6.35) | 0.507 |
Rocuronium Bromide | 82.96 (33.84) | 77.25 (30.76) | 99.29 (41.68) | 0.851 |
Atracurium | 27.71 (20.44) | 26.75 (20.67) | 28.57 (20.56) | 0.577 |
Succinylcholine | 76.79 (18.28) | 76.88 (21.87) | 76.67 (16.33) | 0.985 |
Intraoperative monitoring*** | ||||
pH | 7.40 (0.10) | 7.38 (0.13) | 7.41 (0.04) | 0.113 |
PaO2, mmHg | 220.76 (90.69) | 208.75 (91.30) | 232.31 (90.34) | 0.329 |
PaCO2, mmHg | 37.42 (6.13) | 37.40 (6.78) | 37.45 (5.56) | 0.962 |
Lactate, mmol/L | 1.56 (1.96) | 1.62 (2.70) | 1.29 (0.52) | 0.388 |
Postoperative monitoring | ||||
Fluid delivery postoperative day 1, mean (SD), ml | 2031.97 (1098.29) | 2000.27 (1105.54) | 2061.07 (1109.06) | 0.767 |
ABG at ICU admission | ||||
pH | 7.35 (0.04) | 7.38 (0.05) | 7.36 (0.05) | 0.024 |
PaO2, mmHg | 125.37 (29.74) | 115.71 (39.97) | 146.18 (36.18) | < 0.001 |
PaCO2, mmHg | 41.12 (4.95) | 37.07 (6.31) | 39.19 (6.07) | 0.066 |
Lactate, mmol/L | 1.68 (0.42) | 2.01 (1.55) | 2.77 (2.28) | 0.035 |
ABG when the SBT ends | ||||
pH | 7.38 (0.05) | 7.40 (0.05) | 7.38 (0.05) | 0.063 |
PaO2, mmHg | 112.60 (13.20) | 112.82 (46.07) | 145.86 (31.45) | < 0.001 |
PaCO2, mmHg | 41.95 (2.95) | 38.82 (5.28) | 38.81 (5.19) | 0.986 |
Blood routine examination at ICU admission | ||||
WBC, 10^9/L | 10.96 (4.66) | 12.39 (5.85) | 9.27 (4.42) | 0.002 |
Hemoglobin, mg/L | 111.50 (4.57) | 107.59 (31.79) | 116.70 (19.81) | 0.069 |
Biochemical examination at ICU admission | ||||
Serum albumin, g/L | 33.28 (2.64) | 32.39 (7.19) | 35.21 (7.22) | 0.037 |
Serum creatinine, µmol/L | 217.17 (325.87) | 105.41 (141.33) | 70.92 (39.27) | 0.082 |
CRP, mg/L | 61.01 (99.48) | 92.24 (107.8) | 37.27 (70.45) | 0.002 |
PCT, ng/ml | 1.39 (3.82) | 2.16 (7.00) | 0.53 (1.13) | 0.090 |
Antibiotic delivery, n (%)*** | ||||
Imipenem | 19.00 (16.24) | 15.00 (26.79) | 4.00 (6.56) | 0.003 |
Penicillins and 1st-2nd generation cephalosporins | 74.00 (63.25) | 28.00 (50) | 46.00 (75.41) | 0.004 |
3rd generation cephalosporins/macrolides | 15.00 (12.82) | 11.00 (19.64) | 4.00 (6.56) | 0.034 |
Tetracyclines | 7.00 (5.98) | 6.00 (10.71) | 1.00 (1.64) | 0.172 |
Polypeptide antibiotic | 8.00 (6.84) | 7.00 (12.5) | 1.00 (1.64) | 0.027 |